Drug ClassSulfonylurea + Biguanide (antidiabetic combination)
PrescriptionRequired (Rx)
Habit FormingNo
Overview
Distributor inventory | Tablet
Uses & Benefits
Treatment of type 2 diabetes mellitus in adults when diet and exercise alone or monotherapy is insufficient; helps control high blood sugar.
How It Works
Glimepiride is a sulfonylurea that stimulates the pancreas to release insulin and improves insulin utilization. Metformin reduces glucose production in the liver and improves insulin sensitivity, lowering blood glucose levels.
Directions for Use
Take by mouth exactly as prescribed, usually once daily with breakfast or the first main meal to reduce stomach upset. Swallow the tablet as directed; do not skip meals to avoid low blood sugar. Dose is individualized based on blood glucose and tolerance.
Side Effects
Hypoglycaemia (low blood sugar), nausea, vomiting, diarrhoea, abdominal discomfort, loss of appetite, headache, dizziness, weight gain, metallic taste
Warnings & Precautions
Risk of hypoglycaemia (higher with missed meals, excess exercise, alcohol, or other antidiabetics); monitor blood glucose regularly. Metformin may rarely cause lactic acidosis—seek urgent care for rapid breathing, severe weakness, unusual muscle pain, abdominal pain, or drowsiness; risk increases with kidney/liver disease, dehydration, severe infection, heart failure, or heavy alcohol use. Use with caution/avoid in significant renal impairment; kidney function should be checked before and during therapy. Withhold metformin temporarily around iodinated contrast studies and major surgery as advised by a doctor. Not for type 1 diabetes or diabetic ketoacidosis.
Manufacturer
INTAS PHARMACEUTICALS`
BrandIntas Pharmaceuticals Ltd
Drug Interactions
Alcohol, insulin and other antidiabetics (risk of hypoglycaemia), beta-blockers (may mask hypoglycaemia), ACE inhibitors (may enhance glucose-lowering), corticosteroids and thiazide diuretics (may raise glucose), rifampicin (may reduce effect), fluconazole and other CYP2C9 inhibitors (may increase glimepiride effect), iodinated contrast media (lactic acidosis risk), cimetidine (may increase metformin levels)
Storage Instructions
Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.
Substitutes
Amaryl M 1/500 Tablet, Glycomet-GP 1/500 Tablet, Glimy M 1/500 Tablet, Glucored-GM 1/500 Tablet, Glimestar M1 500 Tablet
Frequently Asked Questions
What is this medicine used for?
Treatment of type 2 diabetes mellitus in adults when diet and exercise alone or monotherapy is insufficient; helps control high blood sugar.
What are the side effects?
Hypoglycaemia (low blood sugar), nausea, vomiting, diarrhoea, abdominal discomfort, loss of appetite, headache, dizziness, weight gain, metallic taste
How does this medicine work?
Glimepiride is a sulfonylurea that stimulates the pancreas to release insulin and improves insulin utilization. Metformin reduces glucose production in the liver and improves insulin sensitivity, lowering blood glucose levels.
How should I use this medicine?
Take by mouth exactly as prescribed, usually once daily with breakfast or the first main meal to reduce stomach upset. Swallow the tablet as directed; do not skip meals to avoid low blood sugar. Dose is individualized based on blood glucose and tolerance.
How should I store this medicine?
Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.
Do I need a prescription for this product?
Yes, this product requires a valid prescription (Rx). Upload it during checkout when prompted.
Can prices or availability change?
Yes. Prices and availability can change based on inventory and serviceability. The latest details are shown at checkout.
How do I place an order?
Select a variant, add to cart, enter delivery address, upload prescription if required, and pay securely.
Manufacturer & Brand
Brand:Intas Pharmaceuticals Ltd
Manufacturer:INTAS PHARMACEUTICALS`
HSN Code:30049099
Alternatives
Alternatives are suggested by pharmacists after reviewing your order and prescription.
Disclaimer: Product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalized guidance.
Sources: Manufacturer labeling, established medical literature (standard pharmacology), CDSCO/Indian drug regulatory labeling practices