Zoryl Ms Ir 2/500MG Tab

Tablet

Type 2 diabetes mellitus in adults when diet and exercise alone or monotherapy is insufficient; helps control blood glucose and HbA1c.

Glimepiride (a sulfonylurea) stimulates the pancreas to release insulin and improves insulin sensitivity. Metformin (a biguanide) reduces glucose production in the liver and improves peripheral glucose uptake, lowering blood sugar without usually causing hypoglycaemia on its own.

Oral tablet. Take exactly as prescribed, usually once or twice daily with meals to reduce stomach upset. Swallow whole with water; do not skip meals. Monitor blood glucose regularly.

Hypoglycaemia, nausea, vomiting, diarrhoea, abdominal pain, loss of appetite, metallic taste, dizziness, headache, weight gain

Risk of hypoglycaemia (higher with missed meals, alcohol, heavy exercise, elderly, kidney/liver impairment). Metformin rarely can cause lactic acidosis—seek urgent care for fast breathing, severe weakness, abdominal pain, or unusual sleepiness. Use with caution/avoid in severe renal impairment, severe hepatic disease, dehydration, severe infection, shock, or hypoxia; temporarily stop before/after iodinated contrast or major surgery as advised. Check kidney function periodically; long-term metformin may cause vitamin B12 deficiency. Not for type 1 diabetes or diabetic ketoacidosis.

Alcohol (increases hypoglycaemia/lactic acidosis risk), iodinated contrast media, insulin/other antidiabetics (additive hypoglycaemia), beta-blockers (mask hypoglycaemia), corticosteroids/thiazides/sympathomimetics (raise glucose), ACE inhibitors (may increase hypoglycaemia), NSAIDs/salicylates (may increase hypoglycaemia), diuretics, cimetidine (may increase metformin levels), certain antibiotics (e.g., sulfonamides/fluoroquinolones may affect glucose)

Store below 25°C in a dry place, protected from moisture and light. Keep in original blister pack and out of reach of children.

Amaryl M 2/500 Tablet, Glycomet-GP 2/500 Tablet, Glimy M 2/500 Tablet, Glimiprex-M 2/500 Tablet, Glimestar M 2/500 Tablet