Zylin D 75+20 Cap

Capsule

Pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute musculoskeletal pain; used when gastric protection is needed with NSAID therapy.

Diclofenac is an NSAID that reduces pain and inflammation by inhibiting COX enzymes and lowering prostaglandin production. Omeprazole is a proton pump inhibitor that decreases stomach acid by blocking the H+/K+ ATPase pump, helping prevent NSAID-associated gastric irritation/ulcers.

Take as prescribed by the doctor. Usually taken once daily; swallow capsule whole with water, preferably before food (especially for better PPI effect). Do not crush or open the capsule. Use the lowest effective dose for the shortest duration.

nausea, stomach pain, indigestion, heartburn, diarrhea, constipation, headache, dizziness, flatulence

NSAIDs can increase risk of stomach/intestinal bleeding, ulceration, and perforation (higher risk in elderly, history of ulcers, alcohol use, or with anticoagulants/steroids). May increase risk of heart attack or stroke with prolonged/high-dose use; use caution in cardiovascular disease, hypertension, edema. Avoid in severe kidney or liver disease unless advised; monitor renal function with prolonged use. Stop and seek care for black stools, vomiting blood, severe abdominal pain, chest pain, shortness of breath, or allergic rash. Long-term PPI use may be associated with low magnesium/B12, fractures, and infections; use as directed.

Anticoagulants/antiplatelets (warfarin, aspirin, clopidogrel), SSRIs/SNRIs, corticosteroids (increased bleeding risk); other NSAIDs; methotrexate, lithium (increased levels/toxicity); ACE inhibitors/ARBs/diuretics (reduced renal function/antihypertensive effect); cyclosporine/tacrolimus (nephrotoxicity); digoxin; omeprazole may interact with clopidogrel (reduced effect), phenytoin, diazepam, warfarin; drugs needing acidic pH (ketoconazole).

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

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