Prescription requiredAnti-acne

A-Ret 0.05 Gel — Side Effects & Warnings

Known side effects of A-Ret 0.05 Gel include Skin irritation, redness, dryness, peeling/flaking, burning/stinging, itching, increased sensitivity to sunlight. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated July 2026

Common Side Effects

Skin irritation
redness
dryness
peeling/flaking
burning/stinging
itching
increased sensitivity to sunlight

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

May cause significant irritation; start with alternate nights if sensitive. Avoid excessive sun/UV exposure; use broad-spectrum sunscreen and protective clothing. Do not apply on cuts, eczema, sunburned or severely irritated skin. Avoid waxing/abrasive cleansers; use gentle skincare. Not for use with other strong irritants unless advised. Stop and seek medical advice if severe swelling, blistering or allergic reaction occurs.

Drug Interactions

A-Ret 0.05 Gel may interact with the following:

Increased irritation with benzoyl peroxide
salicylic acid
sulfur/resorcinol products
astringents/alcohol-containing cosmetics
abrasive soaps/scrubs; photosensitizing agents (e.g.
tetracyclines) may increase sun sensitivity. If using benzoyl peroxide
consider applying at different times (e.g.
benzoyl peroxide morning
tretinoin night) as advised.

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Not recommended / Consult doctor (avoid during pregnancy unless specifically prescribed)

Alcohol Interaction

No known interaction (topical); avoid alcohol-based skincare products on treated areas due to irritation

Habit Forming

Storage

Store below 25°C in a cool, dry place. Protect from light and heat. Keep tube tightly closed and out of reach of children.

A-Ret 0.05 Gel — Safety Summary

Composition: Tretinoin 0.05% w/w topical gel
Prescription: Required (Rx)
Pregnancy: Not recommended / Consult doctor (avoid during pregnancy unless specifically prescribed)
Alcohol: No known interaction (topical); avoid alcohol-based skincare products on treated areas due to irritation
Habit forming: No

A-Ret 0.05 Gel — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.