A-Ret 0.025 Gel
Menarini India Pvt Ltd - Gel - 0.025%W/W - 20 G
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Tretinoin 0.05% w/w topical gel
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A-Ret 0.05 Gel is used for treatment of acne (acne vulgaris), especially blackheads, whiteheads and pimples.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
A-Ret 0.05 Gel contains Tretinoin 0.05% w/w topical gel. It belongs to the Topical retinoid (Vitamin A derivative) class of medicines.
Tretinoin is a topical retinoid that normalizes shedding of skin cells and reduces formation of comedones. It also promotes cell turnover to unclog pores and helps reduce acne lesions over time.
For external use only. Cleanse and dry the affected area; apply a thin layer once daily at night (or as directed by a doctor). Avoid eyes, lips, inside nose and broken/irritated skin; wash hands after use. Use moisturizer and sunscreen in daytime; acne may worsen initially and improvement usually takes several weeks.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.
An overdose of this medicine can cause severe irritation when far too much cream is applied; an oral retinoid taken in excess can cause headache, vomiting and liver injury. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of A-Ret are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Not recommended / Consult doctor (avoid during pregnancy unless specifically prescribed) |
|---|---|
| Breastfeeding | Not recommended while breastfeeding. |
| Alcohol | No known interaction (topical); avoid alcohol-based skincare products on treated areas due to irritation |
| Driving | Not expected to affect your ability to drive. |
| Kidney | Use with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
May cause significant irritation; start with alternate nights if sensitive. Avoid excessive sun/UV exposure; use broad-spectrum sunscreen and protective clothing. Do not apply on cuts, eczema, sunburned or severely irritated skin. Avoid waxing/abrasive cleansers; use gentle skincare. Not for use with other strong irritants unless advised. Stop and seek medical advice if severe swelling, blistering or allergic reaction occurs.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Oral retinoids are absolutely contraindicated in pregnancy and in anyone who might become pregnant without a pregnancy prevention programme. Topical retinoids are avoided in pregnancy.
Increased irritation with benzoyl peroxide, salicylic acid, sulfur/resorcinol products, astringents/alcohol-containing cosmetics, abrasive soaps/scrubs; photosensitizing agents (e.g., tetracyclines) may increase sun sensitivity. If using benzoyl peroxide, consider applying at different times (e.g., benzoyl peroxide morning, tretinoin night) as advised.
Store below 25°C in a cool, dry place. Protect from light and heat. Keep tube tightly closed and out of reach of children.
Apply retinoids at night to clean, dry skin, and moisturise afterwards. Give it at least eight to twelve weeks before judging whether it works. Do not pick or squeeze spots — that is what leaves scars.
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The information on A-Ret 0.05 Gel is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.