OTC · No prescriptionHaematinic / Nutritional supplement

Bi-Folate Aq Inj — Side Effects & Warnings

Known side effects of Bi-Folate Aq Inj include Injection site pain, redness or swelling, nausea, vomiting, diarrhea, headache, dizziness, rash, itching. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

Common Side Effects

Injection site pain
redness or swelling
nausea
vomiting
diarrhea
headache
dizziness
rash
itching

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Use only under medical supervision. Rule out pernicious anemia/isolated vitamin B12 deficiency before giving folic acid alone, as folate may improve anemia while allowing neurological damage from B12 deficiency to progress. Use caution in patients with hypersensitivity to B vitamins/cobalt. If severe allergy (breathing difficulty, swelling, widespread rash) occurs, seek urgent care.

Drug Interactions

Bi-Folate Aq Inj may interact with the following:

Methotrexate
trimethoprim
pyrimethamine (antifolates may reduce folate effect)
phenytoin/phenobarbital/primidone (folate may reduce antiepileptic levels)
chloramphenicol (may blunt hematologic response to B12/folate)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Consult doctor

Alcohol Interaction

Use with caution

Habit Forming

Storage

Store at room temperature (generally below 25°C), protect from light, do not freeze. Keep in original pack and out of reach of children.

Bi-Folate Aq Inj — Safety Summary

Composition: Folic acid (Vitamin B9) + Cyanocobalamin (Vitamin B12) injection (strengths unknown)
Prescription: Not required (OTC)
Pregnancy: Consult doctor
Alcohol: Use with caution
Habit forming: No

Bi-Folate Aq Inj — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.