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Kepler - Syrup - 100 ml
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Folic acid (Vitamin B9) + Cyanocobalamin (Vitamin B12) injection (strengths unknown)
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Bi-Folate Aq Injection is used for treatment and prevention of folate and vitamin B12 deficiency; megaloblastic anemia due to nutritional deficiency; adjunct in deficiency states during pregnancy/lactation as advised by doctor.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Bi-Folate Aq Injection contains Folic acid (Vitamin B9) + Cyanocobalamin (Vitamin B12) injection (strengths unknown). It belongs to the Vitamin (Folic acid) + Vitamin B12 (Cobalamin) class of medicines.
Treatment and prevention of folate and vitamin B12 deficiency; megaloblastic anemia due to nutritional deficiency; adjunct in deficiency states during pregnancy/lactation as advised by doctor.
Folic acid is required for DNA synthesis and red blood cell formation, helping correct megaloblastic anemia due to folate deficiency. Cyanocobalamin (vitamin B12) is essential for normal red blood cell maturation and nerve function and helps treat anemia due to B12 deficiency.
Injection for IM/IV use as prescribed by a doctor. Dose and frequency depend on the deficiency and clinical condition; do not self-administer. Can be given with or without food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Bi-Folate Aq are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Breastfeeding | Generally considered safe while breastfeeding. |
| Alcohol | Use with caution |
| Driving | Not expected to affect your ability to drive. |
| Kidney | Use with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function. |
| Liver | No dose change is usually needed in liver disease. |
| Habit forming | No |
Use only under medical supervision. Rule out pernicious anemia/isolated vitamin B12 deficiency before giving folic acid alone, as folate may improve anemia while allowing neurological damage from B12 deficiency to progress. Use caution in patients with hypersensitivity to B vitamins/cobalt. If severe allergy (breathing difficulty, swelling, widespread rash) occurs, seek urgent care.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack.
Methotrexate, trimethoprim, pyrimethamine (antifolates may reduce folate effect), phenytoin/phenobarbital/primidone (folate may reduce antiepileptic levels), chloramphenicol (may blunt hematologic response to B12/folate)
Store at room temperature (generally below 25°C), protect from light, do not freeze. Keep in original pack and out of reach of children.
A supplement corrects a deficiency; it is not a general energy tonic. If you are on it for nerve symptoms, keep your review appointment so the underlying cause is looked for.

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The information on Bi-Folate Aq Injection is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.