Prescription requiredAnalgesic and Antipyretic

Brufen 400 Tablet — Side Effects & Warnings

Known side effects of Brufen 400 Tablet include Acidity, nausea, stomach pain, heartburn, vomiting, diarrhea, dizziness, headache. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026

Common Side Effects

Acidity
nausea
stomach pain
heartburn
vomiting
diarrhea
dizziness
headache

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Risk of GI bleeding/ulcer especially with prolonged use, older age, alcohol, steroids or blood thinners. Use cautiously in kidney impairment, heart failure, hypertension, liver disease and asthma. Avoid in active peptic ulcer disease and in late pregnancy unless advised.

Drug Interactions

Brufen 400 Tablet may interact with the following:

Warfarin/DOACs
aspirin/clopidogrel
other NSAIDs
steroids
SSRIs/SNRIs
ACE inhibitors/ARBs
diuretics
lithium
methotrexate
cyclosporine

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Use with caution (avoid in 3rd trimester unless prescribed)

Alcohol Interaction

Avoid (higher stomach bleeding risk)

Habit Forming

Storage

Store below 25°C, dry place, away from light and moisture.

Brufen 400 Tablet — Safety Summary

Composition: Ibuprofen 400 mg
Prescription: Required (Rx)
Pregnancy: Use with caution (avoid in 3rd trimester unless prescribed)
Alcohol: Avoid (higher stomach bleeding risk)
Habit forming: No

Brufen 400 Tablet — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

Get help from a doctor

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.