
Antoxipan Ds Sachet
Abbott India Limited - Sachet - 6 G
Ibuprofen 400 mg
Brufen 400 Tablet is used for relief of mild to moderate pain, fever, inflammation in sprain/strain and musculoskeletal pain, dental pain, dysmenorrhea.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Brufen 400 Tablet contains Ibuprofen 400 mg. It belongs to the NSAID (propionic acid derivative) class of medicines.
Ibuprofen is an NSAID that blocks COX enzymes and decreases prostaglandins. This lowers pain sensation, inflammation, and fever.
Take as directed by doctor, preferably after meals. Swallow with water; do not exceed recommended dose. Use lowest effective dose for the shortest duration.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause stomach bleeding, kidney failure, drowsiness and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Brufen are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Use with caution (avoid in 3rd trimester unless prescribed) |
|---|---|
| Breastfeeding | Use with caution while breastfeeding; watch the baby for any unusual symptoms. |
| Alcohol | Avoid (higher stomach bleeding risk) |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Risk of GI bleeding/ulcer especially with prolonged use, older age, alcohol, steroids or blood thinners. Use cautiously in kidney impairment, heart failure, hypertension, liver disease and asthma. Avoid in active peptic ulcer disease and in late pregnancy unless advised.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy.
Warfarin/DOACs, aspirin/clopidogrel, other NSAIDs, steroids, SSRIs/SNRIs, ACE inhibitors/ARBs, diuretics, lithium, methotrexate, cyclosporine
Store below 25°C, dry place, away from light and moisture.
Use the lowest dose for the shortest period. If you need a painkiller regularly, see your doctor rather than continuing on your own. Paracetamol is the safer choice for simple fever and headache.

Abbott India Limited - Sachet - 6 G
Abbott India Limited - Tablet - 15 S

Abbott India Limited - Injection - 6 X1 ml
Prescription required

Abbott India Limited - Injection - 6 X1 ml
Prescription required

Abbott India Limited - 400 iu - 15 ml
Abbott India Limited - 5 ml
Prescription required
Abbott India Limited - Tablet - 15 Tablet

Abbott India Limited - 100 ml
Prescription required

Lewin Healthcare - Tablet - 10 S
Prescription required

Cresha Lifesciences - Tablet - 10 S
Prescription required

Life Gain Pharma - Tablet - 10 S
Prescription required

Albert David Ltd - Tablet - 10 S
Prescription required

Glenmark Pharmaceuticals - Capsule - 10 S
Prescription required

Life Gain Pharma - 30 ml
Prescription required

Mankind (Pharma) - 10 S
Prescription required
Overseas Healthcare - Tablet - 10 S
Prescription required

Icon Pharma - 10 mg - 10 S
Prescription required

East West Pharma - Tablet - 10 mg - 10 S
Prescription required
Glenmark Pharmaceuticals - Tablet - 5 mg - 10 S
Prescription required

Micro Labs - Cream - 15 gm - 15 G
Prescription required

Micro Labs - Capsule - 10 S
Prescription required
Walter Bushnel - 10 mg - 10 S
Prescription required

Brinton Pharmaceuticals Pvt Ltd - Cream - 15 G
Prescription required

Abbott Healthcare Pvt Ltd - Vial - 40 mg - Vial
Prescription required
The information on Brufen 400 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.