Prescription requiredGynecological (Endometriosis therapy)

Dienofem Tab — Side Effects & Warnings

Known side effects of Dienofem Tab include Headache, breast tenderness, nausea, abdominal pain, acne, weight gain, mood changes/depression, decreased libido, irregular vaginal bleeding/spotting. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026

Common Side Effects

Headache
breast tenderness
nausea
abdominal pain
acne
weight gain
mood changes/depression
decreased libido
irregular vaginal bleeding/spotting

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Prescription medicine. Not recommended in pregnancy; rule out pregnancy before starting. Use caution in patients with history of thromboembolic disorders, severe liver disease, liver tumors, unexplained vaginal bleeding, depression, diabetes or cardiovascular risk factors. May cause irregular bleeding, mood changes and rarely blood clots; seek urgent care for chest pain, severe headache, vision changes, leg swelling or breathlessness. Not a contraceptive—use non-hormonal contraception if pregnancy prevention is needed. May reduce bone mineral density with long-term use in some patients; doctor may monitor.

Drug Interactions

Dienofem Tab may interact with the following:

Strong CYP3A4 inducers may reduce effect (rifampicin
carbamazepine
phenytoin
phenobarbital
primidone
St John’s wort); CYP3A4 inhibitors may increase levels (ketoconazole
itraconazole
clarithromycin
ritonavir/cobicistat); use caution with other hormonal therapies/combined oral contraceptives; may affect glucose tolerance with antidiabetics (monitor).

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Not recommended

Alcohol Interaction

Use with caution

Habit Forming

Storage

Store below 25°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.

Dienofem Tab — Safety Summary

Composition: Dienogest (2mg)
Prescription: Required (Rx)
Pregnancy: Not recommended
Alcohol: Use with caution
Habit forming: No

Dienofem Tab — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

Get help from a doctor

Consult a doctor

Discuss side effects with a qualified doctor online.

View all medicines

Full product details for Dienofem Tab.

Lab tests

Book tests to monitor your health while on medication.

Sick leave certificate

Unwell and need rest? A doctor can issue a leave certificate online, from ₹499.

Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.

Dienofem Tab — Side Effects & Warnings

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026