Prescription requiredAnti-asthmatic / COPD (Inhaled corticosteroid + long-acting bronchodilator)

Esiflo 250 Transhaler — Side Effects & Warnings

Known side effects of Esiflo 250 Transhaler include Throat irritation,hoarseness,oral thrush (candidiasis),cough,headache,nausea,tremor,palpitations,upper respiratory tract infection. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026

Common Side Effects

Throat irritation
hoarseness
oral thrush (candidiasis)
cough
headache
nausea
tremor
palpitations
upper respiratory tract infection

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Not for acute bronchospasm or sudden attacks. Use with caution in heart disease, arrhythmias, hypertension, hyperthyroidism, diabetes, glaucoma, osteoporosis, and in patients with seizure disorders. Risk of pneumonia in COPD patients; seek medical help for fever, increased sputum or worsening breathlessness. May cause paradoxical bronchospasm (stop and seek care). Long-term/high-dose inhaled steroids may cause adrenal suppression, reduced bone mineral density, cataract/glaucoma and growth effects in children—use lowest effective dose and monitor.

Drug Interactions

Esiflo 250 Transhaler may interact with the following:

Beta-blockers (may reduce effect/trigger bronchospasm)
other LABA or sympathomimetics (additive effects)
MAO inhibitors/tricyclic antidepressants (may increase cardiovascular effects)
diuretics (risk of hypokalemia)
strong CYP3A4 inhibitors like ritonavir/cobicistat/ketoconazole/itraconazole (increase fluticasone exposure and systemic steroid effects)
other QT-prolonging drugs (caution)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Consult doctor

Alcohol Interaction

No known interaction

Habit Forming

Storage

Store below 25°C, protected from direct sunlight and moisture. Do not freeze. Keep inhaler canister away from heat/flame; do not puncture or burn even when empty. Keep out of reach of children.

Esiflo 250 Transhaler — Safety Summary

Composition: Fluticasone (250mcg) + Salmeterol (25mcg)
Prescription: Required (Rx)
Pregnancy: Consult doctor
Alcohol: No known interaction
Habit forming: No

Esiflo 250 Transhaler — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.