Esiflo 250 Transhaler

Composition of Esiflo 250 Transhaler

Esiflo 250 Transhaler contains Fluticasone (250mcg) + Salmeterol (25mcg). It belongs to the Inhaled corticosteroid (ICS) + Long-acting beta2-agonist (LABA) class of medicines.

Uses of Esiflo 250 Transhaler

Maintenance treatment of asthma; maintenance treatment of COPD (chronic obstructive pulmonary disease) with frequent symptoms/exacerbations as advised by a doctor. Not for relief of sudden breathing attacks.

Key benefits

• Reduces airway inflammation
• Prevents wheezing and breathlessness
• Improves lung function and exercise tolerance
• Decreases frequency of asthma/COPD exacerbations
• Provides long-acting bronchodilation

How Esiflo 250 Transhaler works

Fluticasone is an inhaled corticosteroid that reduces airway inflammation, swelling and mucus production. Formoterol is a long-acting beta2-agonist that relaxes airway smooth muscle to keep the airways open for long-lasting symptom control.

How to take Esiflo 250 Transhaler

For inhalation use only via the Transhaler/MDI as prescribed. Use at the same time each day; do not exceed the prescribed dose. Rinse/gargle mouth and spit after each use to reduce risk of oral thrush. Not a rescue inhaler—keep a reliever (e.g., salbutamol) for acute symptoms.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.

If you take too much

An overdose of this medicine can cause a racing heart, marked tremor, headache and a fall in blood potassium. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Esiflo 250 Transhaler

Most side effects of Esiflo are mild and settle as the body adjusts. Reported side effects include:

• Throat irritation
• hoarseness
• oral thrush (candidiasis)
• cough
• headache
• nausea
• tremor
• palpitations
• upper respiratory tract infection

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Esiflo 250 Transhaler

Warnings and precautions

Not for acute bronchospasm or sudden attacks. Use with caution in heart disease, arrhythmias, hypertension, hyperthyroidism, diabetes, glaucoma, osteoporosis, and in patients with seizure disorders. Risk of pneumonia in COPD patients; seek medical help for fever, increased sputum or worsening breathlessness. May cause paradoxical bronchospasm (stop and seek care). Long-term/high-dose inhaled steroids may cause adrenal suppression, reduced bone mineral density, cataract/glaucoma and growth effects in children—use lowest effective dose and monitor.

Do not take Esiflo if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known allergy to the propellant used in the inhaler.

Interactions with other medicines

Beta-blockers (may reduce effect/trigger bronchospasm),other LABA or sympathomimetics (additive effects),MAO inhibitors/tricyclic antidepressants (may increase cardiovascular effects),diuretics (risk of hypokalemia),strong CYP3A4 inhibitors like ritonavir/cobicistat/ketoconazole/itraconazole (increase fluticasone exposure and systemic steroid effects),other QT-prolonging drugs (caution)

How to store Esiflo 250 Transhaler

Store below 25°C, protected from direct sunlight and moisture. Do not freeze. Keep inhaler canister away from heat/flame; do not puncture or burn even when empty. Keep out of reach of children.

Expert advice for Esiflo 250 Transhaler

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>Esiflo 250 Transhaler is a combination of two medicines that opens the airways and makes it easier to breathe.</li> <li>This medicine is for inhalation only. The tablet should not be swallowed.</li> <li>It should be taken at the same time each day.</li> <li>It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing. </li> <li>Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.</li> <li>Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.</li> <li>Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.</li> <li>Your doctor may regularly monitor your blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Esiflo 250 Transhaler can lower blood potassium level.</li> <li>Only miniscule amounts of Esiflo 250 Transhaler may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:

Lupin Ltd

Therapeutic class:

Anti-asthmatic / COPD (Inhaled corticosteroid + long-acting bronchodilator)

Drug class:

Inhaled corticosteroid (ICS) + Long-acting beta2-agonist (LABA)