Estrabet 1 mg Tablet

Composition of Estrabet 1 mg Tablet

Estrabet 1 mg Tablet contains Estradiol 1 mg (as Estradiol/estradiol hemihydrate) tablet. It belongs to the Estrogen (sex hormone) class of medicines.

Uses of Estrabet 1 mg Tablet

• Hormone replacement therapy (HRT) for symptoms of menopause (hot flashes
• night sweats
• vaginal dryness) and prevention of postmenopausal osteoporosis when appropriate; treatment of estrogen deficiency (e.g.
• due to ovarian failure or after oophorectomy) as advised by a doctor.

Key benefits

• Relieves hot flashes and night sweats
• Improves vaginal dryness and discomfort
• Helps prevent postmenopausal bone loss
• Replaces estrogen in estrogen-deficiency states

How Estrabet 1 mg Tablet works

Estradiol is a natural estrogen hormone. It replaces or supplements estrogen levels that fall after menopause or due to ovarian insufficiency, helping relieve vasomotor and urogenital symptoms and maintaining bone mineral density. It acts by binding to estrogen receptors and regulating gene expression in target tissues.

How to take Estrabet 1 mg Tablet

Take by mouth as prescribed, usually once daily at the same time each day. Can be taken with or without food. Swallow with water; do not exceed the prescribed dose. HRT regimens may be cyclic or continuous; if you have a uterus, a progestogen is often added to reduce endometrial cancer risk.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine may cause nausea, vomiting and withdrawal bleeding. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Estrabet 1 mg Tablet

Most side effects of Estrabet are mild and settle as the body adjusts. Reported side effects include:

• nausea
• headache
• breast tenderness
• abdominal pain
• bloating
• fluid retention (edema)
• vaginal bleeding/spotting
• mood changes
• dizziness

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Estrabet 1 mg Tablet

Warnings and precautions

Prescription-only hormone. Increased risk of blood clots (DVT/PE), stroke and heart attack (especially with risk factors such as smoking, obesity, immobility, thrombophilia). May increase risk of breast cancer with long-term use and risk of endometrial hyperplasia/cancer if used without progestogen in women with an intact uterus. Avoid/use only under specialist advice in history of breast/estrogen-dependent cancer, unexplained vaginal bleeding, active or past VTE, severe liver disease, porphyria, or pregnancy. Stop and seek urgent care for chest pain, sudden breathlessness, severe headache, vision changes, leg swelling/pain, or jaundice. Regular follow-up (breast exam/mammography as advised, BP, and evaluation of abnormal bleeding).

Do not take Estrabet if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with a history of blood clots, certain hormone-sensitive cancers, or active liver disease. Several are contraindicated in pregnancy.

Interactions with other medicines

CYP3A4 inducers may reduce effect (rifampicin, rifabutin, carbamazepine, phenytoin, phenobarbital, primidone, St John’s wort); CYP3A4 inhibitors may increase levels (ketoconazole/itraconazole, erythromycin/clarithromycin, ritonavir/cobicistat); may affect thyroid hormone requirements (increase TBG—monitor if on levothyroxine); may alter effects of anticoagulants and corticosteroids—monitor.

How to store Estrabet 1 mg Tablet

Store below 25°C in a cool, dry place. Protect from moisture and light. Keep in original blister and out of reach of children.

Expert advice for Estrabet 1 mg Tablet

Set a daily alarm if you take it for contraception. Keep your review appointments — blood pressure and other checks matter on long-term hormones.

Manufacturer and class

Manufacturer:

ABBOTT INDIA LTD

Therapeutic class:

Hormone therapy (HRT)

Drug class:

Estrogen (sex hormone)