Prescription requiredAntidiabetic

Gli 2 Met Tab — Side Effects & Warnings

Known side effects of Gli 2 Met Tab include Hypoglycaemia (low blood sugar),nausea,diarrhoea,abdominal pain,loss of appetite,metallic taste,headache,dizziness,weight gain (with glimepiride). Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026

Common Side Effects

Hypoglycaemia (low blood sugar)
nausea
diarrhoea
abdominal pain
loss of appetite
metallic taste
headache
dizziness
weight gain (with glimepiride)

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

May cause hypoglycaemia—higher risk with missed meals, excess exercise, alcohol, elderly, or with other antidiabetics; carry glucose/sugar source. Use caution in kidney or liver disease; metformin is not recommended in severe renal impairment due to risk of lactic acidosis. Temporarily stop metformin before/after iodinated contrast procedures or major surgery as advised by doctor. Seek urgent care for symptoms of lactic acidosis (deep/rapid breathing, severe weakness, persistent vomiting, abdominal pain).

Drug Interactions

Gli 2 Met Tab may interact with the following:

Alcohol (increases risk of hypoglycaemia and lactic acidosis)
iodinated contrast media (metformin)
other antidiabetics/insulin (additive hypoglycaemia)
beta-blockers (mask hypoglycaemia symptoms)
corticosteroids and thiazide diuretics (raise blood sugar)
ACE inhibitors (may increase hypoglycaemia risk)
fluoroquinolones (blood sugar disturbances)
cimetidine (may increase metformin levels)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Not recommended; consult doctor (often switched to insulin during pregnancy)

Alcohol Interaction

Avoid

Habit Forming

Storage

Store below 25°C in a cool, dry place away from moisture and direct light. Keep in original pack and out of reach of children.

Gli 2 Met Tab — Safety Summary

Composition: Glimepiride 2 mg + Metformin Hydrochloride 500 mg (usually sustained/extended release; exact release type not specified)
Prescription: Required (Rx)
Pregnancy: Not recommended; consult doctor (often switched to insulin during pregnancy)
Alcohol: Avoid
Habit forming: No

Gli 2 Met Tab — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.

Gli 2 Met Tab — Side Effects & Warnings

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026