Prescription requiredAntidiabetic

GLIMIPREX SM 1/50/500MG TAB — Side Effects & Warnings

Known side effects of GLIMIPREX SM 1/50/500MG TAB include Hypoglycaemia (low blood sugar),nausea,diarrhoea,abdominal discomfort,loss of appetite,headache,dizziness,weight gain (may occur),upper respiratory tract infection. Not everyone experiences these side effects.

Common Side Effects

Hypoglycaemia (low blood sugar)
nausea
diarrhoea
abdominal discomfort
loss of appetite
headache
dizziness
weight gain (may occur)
upper respiratory tract infection

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Risk of hypoglycaemia (higher with missed meals, alcohol, heavy exercise, elderly, kidney/liver disease); metformin-associated lactic acidosis is rare but serious—seek urgent care for fast breathing, severe weakness, abdominal pain, or unusual sleepiness; avoid/use with caution in renal impairment—dose adjustment and periodic kidney function tests needed; temporarily stop metformin before/after iodinated contrast procedures or major surgery as advised by doctor; sitagliptin may rarely cause pancreatitis—report severe persistent abdominal pain; use caution in hepatic impairment; not for type 1 diabetes or diabetic ketoacidosis.

Drug Interactions

GLIMIPREX SM 1/50/500MG TAB may interact with the following:

Alcohol (increases hypoglycaemia and lactic acidosis risk)
insulin/other antidiabetics (additive hypoglycaemia)
corticosteroids and diuretics (may increase glucose)
beta-blockers (mask hypoglycaemia symptoms)
ACE inhibitors (may increase hypoglycaemia)
iodinated contrast media (lactic acidosis risk with metformin)
cimetidine (may increase metformin levels)
rifampicin (may alter sitagliptin exposure)
strong CYP2C9 inhibitors/inducers (may affect glimepiride levels)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Consult doctor (generally not recommended; insulin is preferred in pregnancy)

Alcohol Interaction

Avoid

Habit Forming

Storage

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

GLIMIPREX SM 1/50/500MG TAB — Safety Summary

Composition: Glimepiride 1 mg + Sitagliptin 50 mg + Metformin Hydrochloride 500 mg (usually as sustained/extended-release; check pack label)
Prescription: Required (Rx)
Pregnancy: Consult doctor (generally not recommended; insulin is preferred in pregnancy)
Alcohol: Avoid
Habit forming: No

GLIMIPREX SM 1/50/500MG TAB — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.