Prescription requiredAntidiabetic

Glimisave M2 750 Tablet — Side Effects & Warnings

Known side effects of Glimisave M2 750 Tablet include Nausea, vomiting, diarrhoea, abdominal pain, loss of appetite, metallic taste, headache, dizziness, hypoglycaemia (low blood sugar), weight gain, skin rash. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026

Common Side Effects

Nausea
vomiting
diarrhoea
abdominal pain
loss of appetite
metallic taste
headache
dizziness
hypoglycaemia (low blood sugar)
weight gain
skin rash

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Schedule H: use on prescription only. Risk of hypoglycaemia (especially with missed meals, excess exercise, alcohol, or with other antidiabetics); carry sugar/glucose. Metformin may rarely cause lactic acidosis—risk increases with kidney disease, dehydration, severe infection, shock, alcohol use, or hypoxia; stop and seek care if rapid breathing, severe weakness, abdominal pain, or drowsiness occur. Avoid/adjust in renal impairment; monitor eGFR, liver function, and vitamin B12 with long-term use. Temporarily stop metformin before/at time of iodinated contrast procedures or major surgery and restart only when kidney function is stable. Use caution in elderly and in people with G6PD deficiency (rare haemolysis with sulfonylureas).

Drug Interactions

Glimisave M2 750 Tablet may interact with the following:

Alcohol (increases hypoglycaemia and lactic acidosis risk)
insulin/other antidiabetics (additive hypoglycaemia)
beta-blockers (mask hypoglycaemia symptoms)
ACE inhibitors (may increase hypoglycaemia)
corticosteroids/thiazide diuretics/sympathomimetics (raise blood glucose)
fluoroquinolones (blood glucose disturbances)
azole antifungals and macrolides (may enhance glimepiride effect)
rifampicin (may reduce glimepiride effect)
iodinated contrast media (lactic acidosis risk)
cimetidine (may increase metformin levels)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Consult doctor (generally not recommended; insulin is preferred in pregnancy)

Alcohol Interaction

Avoid

Habit Forming

Storage

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

Glimisave M2 750 Tablet — Safety Summary

Composition: Glimepiride 2 mg + Metformin Hydrochloride 750 mg (modified release)
Prescription: Required (Rx)
Pregnancy: Consult doctor (generally not recommended; insulin is preferred in pregnancy)
Alcohol: Avoid
Habit forming: No

Glimisave M2 750 Tablet — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

Get help from a doctor

Consult a doctor

Discuss side effects with a qualified doctor online.

View all medicines

Full product details for Glimisave M2 750 Tablet.

Lab tests

Book tests to monitor your health while on medication.

Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.

Glimisave M2 750 Tablet — Side Effects & Warnings

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026