Glimisave M2 750 Tablet

Composition of Glimisave M2 750 Tablet

Glimisave M2 750 Tablet contains Glimepiride 2 mg + Metformin Hydrochloride 750 mg (modified release). It belongs to the Sulfonylurea + Biguanide (Metformin SR) class of medicines.

Uses of Glimisave M2 750 Tablet

Type 2 diabetes mellitus: to control high blood sugar in adults when diet and exercise alone are not sufficient; helps prevent diabetes-related complications.

Key benefits

• Lowers blood sugar levels
• Improves insulin secretion and sensitivity
• Helps control fasting and post-meal glucose
• Reduces risk of diabetes-related complications
• Convenient once-daily modified-release metformin regimen

How Glimisave M2 750 Tablet works

Glimepiride (a sulfonylurea) increases insulin release from the pancreas. Metformin (a biguanide) reduces glucose production in the liver and improves insulin sensitivity, decreasing intestinal glucose absorption. Together they lower fasting and post-meal blood glucose.

How to take Glimisave M2 750 Tablet

Tablet (modified release): take exactly as prescribed, usually once daily with or just after food (preferably breakfast). Swallow whole; do not crush or chew. Maintain diet/exercise and monitor blood sugar; if a dose is missed, take the next dose at the usual time (do not double).

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Glimisave M2 750 Tablet

Most side effects of Glimisave M2 are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• diarrhoea
• abdominal pain
• loss of appetite
• metallic taste
• headache
• dizziness
• hypoglycaemia (low blood sugar)
• weight gain
• skin rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Glimisave M2 750 Tablet

Warnings and precautions

Schedule H: use on prescription only. Risk of hypoglycaemia (especially with missed meals, excess exercise, alcohol, or with other antidiabetics); carry sugar/glucose. Metformin may rarely cause lactic acidosis—risk increases with kidney disease, dehydration, severe infection, shock, alcohol use, or hypoxia; stop and seek care if rapid breathing, severe weakness, abdominal pain, or drowsiness occur. Avoid/adjust in renal impairment; monitor eGFR, liver function, and vitamin B12 with long-term use. Temporarily stop metformin before/at time of iodinated contrast procedures or major surgery and restart only when kidney function is stable. Use caution in elderly and in people with G6PD deficiency (rare haemolysis with sulfonylureas).

Do not take Glimisave M2 if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Alcohol (increases hypoglycaemia and lactic acidosis risk), insulin/other antidiabetics (additive hypoglycaemia), beta-blockers (mask hypoglycaemia symptoms), ACE inhibitors (may increase hypoglycaemia), corticosteroids/thiazide diuretics/sympathomimetics (raise blood glucose), fluoroquinolones (blood glucose disturbances), azole antifungals and macrolides (may enhance glimepiride effect), rifampicin (may reduce glimepiride effect), iodinated contrast media (lactic acidosis risk), cimetidine (may increase metformin levels)

How to store Glimisave M2 750 Tablet

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

Expert advice for Glimisave M2 750 Tablet

Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

Manufacturer and class

Manufacturer:

ERIS LIFE SCIENCES PVT LTD

Therapeutic class:

Antidiabetic

Drug class:

Sulfonylurea + Biguanide (Metformin SR)