Prescription requiredAntidiabetic

Glycomet Trio 1 Forte — Side Effects & Warnings

Known side effects of Glycomet Trio 1 Forte include Hypoglycaemia, nausea, diarrhoea, abdominal pain, flatulence, bloating, metallic taste, headache, dizziness, weight gain. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

Common Side Effects

Hypoglycaemia
nausea
diarrhoea
abdominal pain
flatulence
bloating
metallic taste
headache
dizziness
weight gain

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Risk of hypoglycaemia (higher with missed meals, alcohol, strenuous exercise, elderly); monitor blood glucose. Metformin may rarely cause lactic acidosis—risk increases with kidney impairment, dehydration, severe infection, alcohol use, heart/respiratory failure; assess renal function before and during therapy. Avoid in severe renal or hepatic impairment; use caution in heart failure. Temporarily stop metformin before/after iodinated contrast or major surgery as advised by doctor. Seek help for symptoms of low sugar (sweating, tremor, confusion) or lactic acidosis (deep rapid breathing, severe weakness, abdominal pain).

Drug Interactions

Glycomet Trio 1 Forte may interact with the following:

Alcohol (increases hypoglycaemia/lactic acidosis risk)
iodinated contrast media
insulin/other antidiabetics (additive hypoglycaemia)
sulfonylureas/repaglinide (hypoglycaemia)
beta-blockers (mask hypoglycaemia)
corticosteroids/thyroid hormones/diuretics (raise glucose)
ACE inhibitors (may increase hypoglycaemia)
cimetidine and other OCT2/MATE inhibitors (increase metformin levels)
NSAIDs and nephrotoxic drugs (worsen kidney function)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Not recommended; consult doctor (insulin usually preferred in pregnancy)

Alcohol Interaction

Avoid

Habit Forming

Storage

Store at room temperature (below 25°C), protected from moisture and light. Keep in original strip and out of reach of children.

Glycomet Trio 1 Forte — Safety Summary

Composition: Glimepiride 2 mg + Metformin hydrochloride (sustained release) 1000 mg + Voglibose 0.3 mg tablets
Prescription: Required (Rx)
Pregnancy: Not recommended; consult doctor (insulin usually preferred in pregnancy)
Alcohol: Avoid
Habit forming: No

Glycomet Trio 1 Forte — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.