Prescription requiredAntidiabetic

Glycomet Trio 2 Forte — Side Effects & Warnings

Known side effects of Glycomet Trio 2 Forte include Nausea, vomiting, diarrhoea, abdominal pain, flatulence, loss of appetite, headache, dizziness, hypoglycaemia, weight gain, taste disturbance. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

Common Side Effects

Nausea
vomiting
diarrhoea
abdominal pain
flatulence
loss of appetite
headache
dizziness
hypoglycaemia
weight gain
taste disturbance

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Risk of hypoglycaemia (higher with missed meals, alcohol, strenuous exercise); lactic acidosis risk with metformin (seek help for rapid breathing, severe weakness, abdominal pain). Use caution/avoid in severe kidney impairment; assess renal function before and during treatment. Avoid in severe liver disease, severe infection, dehydration, shock, or hypoxic states. Stop temporarily before/after iodinated contrast or major surgery as advised. Not for type 1 diabetes or diabetic ketoacidosis.

Drug Interactions

Glycomet Trio 2 Forte may interact with the following:

Alcohol (increases hypoglycaemia/lactic acidosis risk)
insulin/other antidiabetics (additive hypoglycaemia)
beta-blockers (mask hypoglycaemia symptoms)
corticosteroids/diuretics (raise glucose)
ACE inhibitors (may increase hypoglycaemia)
fluoroquinolones (glucose disturbances)
cimetidine (may increase metformin levels)
iodinated contrast media (kidney injury/lactic acidosis risk)
warfarin (possible effect changes)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Consult doctor (generally not recommended; insulin preferred in pregnancy)

Alcohol Interaction

Avoid

Habit Forming

Storage

Store below 25°C in a dry place. Protect from moisture and light. Keep out of reach of children.

Glycomet Trio 2 Forte — Safety Summary

Composition: Glimepiride 2 mg + Metformin hydrochloride 1000 mg (sustained/extended release) + Voglibose 0.3 mg tablet
Prescription: Required (Rx)
Pregnancy: Consult doctor (generally not recommended; insulin preferred in pregnancy)
Alcohol: Avoid
Habit forming: No

Glycomet Trio 2 Forte — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.

Glycomet Trio 2 Forte — Side Effects & Warnings

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026