Glycomet Trio 2 Forte

Composition of Glycomet Trio 2 Forte

Glycomet Trio 2 Forte contains Glimepiride 2 mg + Metformin hydrochloride 1000 mg (sustained/extended release) + Voglibose 0.3 mg tablet. It belongs to the Sulfonylurea + Biguanide + Alpha-glucosidase inhibitor class of medicines.

Uses of Glycomet Trio 2 Forte

Type 2 diabetes mellitus (when diet and exercise alone or dual therapy is insufficient); helps control post‑meal and fasting blood glucose

Key benefits

• Lowers fasting and post‑meal blood glucose
• Improves insulin secretion and sensitivity
• Reduces hepatic glucose production
• Helps reduce post‑prandial glucose spikes
• Supports long‑term glycaemic control (HbA1c)

How Glycomet Trio 2 Forte works

Glimepiride increases insulin release from the pancreas and improves insulin sensitivity. Metformin reduces glucose production in the liver and improves peripheral glucose uptake. Voglibose delays intestinal carbohydrate absorption, lowering post‑meal glucose spikes.

How to take Glycomet Trio 2 Forte

Take orally as prescribed, usually once daily with the first main meal (or as advised). Swallow whole; do not crush/chew (metformin SR/ER). Take with food to reduce stomach upset; monitor blood glucose regularly.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar and marked stomach upset. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Glycomet Trio 2 Forte

Most side effects of Glycomet Trio are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• diarrhoea
• abdominal pain
• flatulence
• loss of appetite
• headache
• dizziness
• hypoglycaemia
• weight gain
• taste disturbance

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Glycomet Trio 2 Forte

Warnings and precautions

Risk of hypoglycaemia (higher with missed meals, alcohol, strenuous exercise); lactic acidosis risk with metformin (seek help for rapid breathing, severe weakness, abdominal pain). Use caution/avoid in severe kidney impairment; assess renal function before and during treatment. Avoid in severe liver disease, severe infection, dehydration, shock, or hypoxic states. Stop temporarily before/after iodinated contrast or major surgery as advised. Not for type 1 diabetes or diabetic ketoacidosis.

Do not take Glycomet Trio if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for people with heart failure, active bladder cancer or unexplained blood in the urine.

Interactions with other medicines

Alcohol (increases hypoglycaemia/lactic acidosis risk), insulin/other antidiabetics (additive hypoglycaemia), beta-blockers (mask hypoglycaemia symptoms), corticosteroids/diuretics (raise glucose), ACE inhibitors (may increase hypoglycaemia), fluoroquinolones (glucose disturbances), cimetidine (may increase metformin levels), iodinated contrast media (kidney injury/lactic acidosis risk), warfarin (possible effect changes)

How to store Glycomet Trio 2 Forte

Store below 25°C in a dry place. Protect from moisture and light. Keep out of reach of children.

Expert advice for Glycomet Trio 2 Forte

Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them. Take it with the first mouthful of your meal so it can act on that meal. Expect some wind in the first weeks; it usually settles.

Manufacturer and class

Manufacturer:

USV LIMITED

Therapeutic class:

Antidiabetic

Drug class:

Sulfonylurea + Biguanide + Alpha-glucosidase inhibitor