Prescription requiredAntidiabetic

Glypride 1 Tablet — Side Effects & Warnings

Known side effects of Glypride 1 Tablet include Hypoglycaemia (low blood sugar), dizziness, headache, nausea, abdominal pain, diarrhoea, weight gain, skin rash. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026

Common Side Effects

Hypoglycaemia (low blood sugar)
dizziness
headache
nausea
abdominal pain
diarrhoea
weight gain
skin rash

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Risk of hypoglycaemia—more likely with missed meals, excessive exercise, alcohol intake, elderly, or kidney/liver impairment; carry a quick source of glucose. Use with caution in renal/hepatic disease and in patients with G6PD deficiency (risk of haemolysis). Not for type 1 diabetes or diabetic ketoacidosis. Monitor blood glucose/HbA1c regularly. Inform doctor before surgery/acute illness; dose changes may be needed. Rare but serious: severe allergic reactions, liver problems, blood count changes—seek care if jaundice, dark urine, unusual bruising/bleeding occur.

Drug Interactions

Glypride 1 Tablet may interact with the following:

Other antidiabetics/insulin (increased hypoglycaemia)
alcohol (increased risk of hypoglycaemia)
beta-blockers (may mask hypoglycaemia symptoms)
ACE inhibitors (may enhance glucose-lowering)
corticosteroids/thiazide diuretics/sympathomimetics (may raise glucose)
azole antifungals (e.g.
fluconazole)
macrolides (e.g.
clarithromycin)
quinolones
NSAIDs and salicylates (may increase hypoglycaemia)
rifampicin and phenytoin (may reduce effect)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Not recommended; consult doctor (insulin is generally preferred in pregnancy)

Alcohol Interaction

Avoid (can increase risk of low blood sugar)

Habit Forming

Storage

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep in original strip and out of reach of children.

Glypride 1 Tablet — Safety Summary

Composition: Glimepiride 1 mg
Prescription: Required (Rx)
Pregnancy: Not recommended; consult doctor (insulin is generally preferred in pregnancy)
Alcohol: Avoid (can increase risk of low blood sugar)
Habit forming: No

Glypride 1 Tablet — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.