Itrasol 200

Composition of Itrasol 200

Itrasol 200 contains Itraconazole (200mg). It belongs to the Triazole antifungal (CYP3A4 inhibitor) class of medicines.

Uses of Itrasol 200

• Treatment of fungal infections such as aspergillosis
• histoplasmosis
• blastomycosis; dermatophytosis (tinea/ringworm)
• pityriasis versicolor; candidiasis (oral/esophageal/vaginal); onychomycosis (nail fungal infection) as prescribed.

Key benefits

• Treats skin fungal infections (tinea)
• Treats candidiasis
• Helps in nail fungal infection (onychomycosis)
• Used for systemic fungal infections

How Itrasol 200 works

Itraconazole is a triazole antifungal that inhibits fungal CYP450 enzyme 14-alpha-demethylase, reducing ergosterol synthesis. This disrupts the fungal cell membrane and stops fungal growth, leading to clearance of infection.

How to take Itrasol 200

Capsule: take exactly as prescribed. Usually taken with food (better absorption); swallow whole and do not crush/chew. Take at the same time each day; duration depends on infection type and site. Avoid taking with acid-suppressing medicines unless advised.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Itrasol 200mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause vomiting, liver injury and heart rhythm disturbance. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Itrasol 200

Most side effects of Itrasol are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• abdominal pain
• diarrhea
• headache
• dizziness
• rash
• elevated liver enzymes
• peripheral edema

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Itrasol 200

Warnings and precautions

Prescription-only antifungal. Can cause liver injury—seek care for jaundice, dark urine, severe fatigue; monitoring may be needed, especially with prolonged therapy. May worsen or precipitate heart failure—avoid/use with extreme caution in patients with ventricular dysfunction/CHF. Numerous serious drug interactions due to strong CYP3A4 inhibition; do not self-medicate. Use caution in kidney/liver disease and in the elderly.

Do not take Itrasol if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with active liver disease, and several are not for use in pregnancy. Itraconazole is not for people with heart failure.

Interactions with other medicines

Strong interactions via CYP3A4: statins (simvastatin/lovastatin), antiarrhythmics (quinidine, dofetilide, dronedarone), benzodiazepines (midazolam, triazolam), ergot alkaloids, certain antihistamines (terfenadine/astemizole), some calcium channel blockers, warfarin, digoxin, cyclosporine/tacrolimus, oral hypoglycemics. Reduced absorption with PPIs/H2 blockers/antacids. Rifampicin, phenytoin, carbamazepine, efavirenz reduce itraconazole levels.

How to store Itrasol 200

Store below 25°C in a dry place, protected from moisture and light. Keep in original pack and out of reach of children.

Expert advice for Itrasol 200

Itrasol 200mg Tablet helps treat fungal infections of mouth, skin, vagina or any other parts of the body. Do not skip any doses and finish the full course of treatment even if you feel better. Take it with food, preferably at the same time everyday. Use a reliable method of contraception to prevent pregnancy while taking this medicine. Do not take indigestion remedies (antacids) within 2 hours of taking Itrasol 200mg Tablet. Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain. Inform your doctor if you develop allergic reactions, nerve pain, or hearing loss. Your doctor has prescribed Itrasol 200mg Tablet to cure your infection and improve symptoms. Do not skip any doses and finish the full course of treatment even if you feel better.

Manufacturer and class

Manufacturer:

CRESOL PHARMACEUTICALS PVT LTD

Therapeutic class:

Antifungal

Drug class:

Triazole antifungal (CYP3A4 inhibitor)

Chemical class:

Phenylpiperazines