Itrasys 100 mg

Composition of Itrasys 100 mg

Itrasys 100 mg contains Itraconazole 100 mg (capsule). It belongs to the Triazole antifungal class of medicines.

Uses of Itrasys 100 mg

• Treatment of fungal infections such as aspergillosis
• blastomycosis
• histoplasmosis
• onychomycosis (nail fungus)
• tinea (ringworm)
• candidiasis and other susceptible systemic or superficial mycoses

Key benefits

• Treats systemic fungal infections
• Effective for skin and nail fungal infections
• Helps clear candidal infections
• Prevents fungal cell membrane formation
• Reduces itching and lesions caused by dermatophytes

How Itrasys 100 mg works

Itraconazole is a triazole antifungal that inhibits fungal CYP450-dependent synthesis of ergosterol, an essential component of the fungal cell membrane. This disrupts membrane integrity and stops fungal growth and replication.

How to take Itrasys 100 mg

Take as directed by a doctor. Capsules are usually taken with food for better absorption; swallow whole with water. Take at the same time each day and complete the full course even if symptoms improve.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause vomiting, liver injury and heart rhythm disturbance. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Itrasys 100 mg

Most side effects of Itrasys are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• abdominal pain
• diarrhoea
• headache
• dizziness
• rash
• raised liver enzymes

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Itrasys 100 mg

Warnings and precautions

Not recommended in patients with heart failure/ventricular dysfunction; seek medical advice if shortness of breath, swelling or sudden weight gain occurs. Use with caution in liver disease; liver function monitoring may be needed and stop if symptoms of hepatitis (fatigue, loss of appetite, dark urine, jaundice) appear. Avoid use in pregnancy unless clearly needed; effective contraception advised during treatment and for some time after. Many significant drug interactions—inform your doctor about all medicines. Acid-reducing agents can lower absorption; take as advised.

Do not take Itrasys if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with active liver disease, and several are not for use in pregnancy. Itraconazole is not for people with heart failure.

Interactions with other medicines

Contraindicated/major interactions with simvastatin/lovastatin, quinidine, dofetilide, dronedarone, ergot alkaloids, oral midazolam/triazolam, certain calcium channel blockers, some antiarrhythmics. Increases levels of warfarin, digoxin, cyclosporine/tacrolimus, certain benzodiazepines, sulfonylureas. Rifampicin/rifabutin, phenytoin, carbamazepine, St John’s wort reduce itraconazole levels. PPIs/H2 blockers/antacids may reduce absorption of capsules.

How to store Itrasys 100 mg

Store below 25°C in a cool, dry place away from moisture and direct light. Keep in original pack and out of reach of children.

Expert advice for Itrasys 100 mg

Complete the full course, however long. Keep the skin clean and dry, wash clothes and bedding in hot water, and treat family members if they are affected, or reinfection is very likely.

Manufacturer and class

Manufacturer:

SYSTOPIC LAB

Therapeutic class:

Antifungal

Drug class:

Triazole antifungal