Prescription requiredAnti-rheumatic (DMARD)

LEFUPRO 20MG TAB — Side Effects & Warnings

Known side effects of LEFUPRO 20MG TAB include Diarrhoea, nausea, abdominal pain, headache, dizziness, rash, hair thinning/alopecia, elevated liver enzymes, hypertension, respiratory infections. Not everyone experiences these side effects.

Common Side Effects

Diarrhoea
nausea
abdominal pain
headache
dizziness
rash
hair thinning/alopecia
elevated liver enzymes
hypertension
respiratory infections

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Not recommended in pregnancy; causes severe birth defects—effective contraception is required during treatment and until drug is eliminated (may require cholestyramine/activated charcoal washout). Avoid breastfeeding. Risk of serious liver injury—do not use in severe hepatic impairment; avoid alcohol; monitor LFTs. Can cause bone marrow suppression/infections—monitor CBC; avoid live vaccines. Use caution in hypertension and lung disease (rare interstitial lung disease). Discuss washout before planned pregnancy (women and men) or before switching to another hepatotoxic/immunosuppressive drug.

Drug Interactions

LEFUPRO 20MG TAB may interact with the following:

Methotrexate and other hepatotoxic drugs (increased liver toxicity)
warfarin (may alter INR)
rifampicin (may increase active metabolite levels)
cholestyramine/activated charcoal (markedly decreases levels; used for washout)
live vaccines (reduced response/infection risk)
other immunosuppressants (additive infection risk)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Not recommended

Alcohol Interaction

Avoid

Habit Forming

Storage

Store below 25°C in a dry place, protected from moisture and light. Keep in original pack and out of reach of children.

LEFUPRO 20MG TAB — Safety Summary

Composition: Leflunomide 20 mg
Prescription: Required (Rx)
Pregnancy: Not recommended
Alcohol: Avoid
Habit forming: No

LEFUPRO 20MG TAB — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.