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Prescription requiredBrinton Pharmaceuticals Pvt LtdAnti-rheumatic (DMARD)

Lefupro 20 mg Tablet

Leflunomide 20 mg

Currently out of stock

Same composition, in stock now. Check with your doctor or pharmacist before you switch.

  • Lefra 10 Tablet₹170View
  • Cleft 20 mg Tablet₹228View
  • Lefutoid 20 mg Tablet₹275View

Lefupro 20 mg Tablet is used for treatment of active rheumatoid arthritis; may also be used in psoriatic arthritis as prescribed.

Licensed pharmacyPharmacist-verified order

Key details

Salt: Leflunomide 20 mg
Available variants: tablet 20 mg 10`S
Price: ₹228 (₹22.77 per tablet)
Prescription: Required
Manufacturer: BRINTON PHARMACEUTICALS

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Lefupro 20 mg Tablet in Bangladesh

8 brands registered in Bangladesh with the same salt, strength and form.

  • ArolefGeneral Pharmaceuticals Ltd.
  • DimarOpsonin Pharma Limited
  • LefluAlco Pharma Limited
  • LemaMystic Pharmaceuticals Ltd.
  • LeraGlobe Pharmaceuticals Ltd.
  • MotoralAdvanced Chemical Industries PLC.
  • NodiaIncepta Pharmaceuticals Ltd.
  • SynomidBeximco Pharmaceuticals Ltd.

Brand names differ between countries. Ask a pharmacist or your doctor in Bangladesh before switching. We don't sell or ship these brands. Source: Directorate General of Drug Administration, Bangladesh.

Compare medicine alternatives

Medicines with the same active ingredient and strength as Lefupro 20 mg Tablet.

You are viewing

Lefupro 20 mg Tablet

tablet - 20 mg - 10 S

₹228

₹22.77 per tablet

  • Lefra 10 Tablet

    Torrent Pharmaceuticals Ltd · tablet - 20mg - 10 S · Rx

    ₹170

    ₹16.98 per tablet

    Save 25%
Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Lefupro 20 mg Tablet. The brand name, manufacturer, inactive ingredients and price can differ, and so can release form, so a substitute is not automatically interchangeable.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Lefupro 20 mg Tablet

Lefupro 20 mg Tablet contains Leflunomide 20 mg. It belongs to the Pyrimidine synthesis inhibitor (DMARD; dihydroorotate dehydrogenase inhibitor) class of medicines.

Uses of Lefupro 20 mg Tablet

  • Active rheumatoid arthritis
  • May also be used in psoriatic arthritis as prescribed

Benefits of Lefupro 20 mg Tablet

In Pain and swelling
Lefupro reduces pain and swelling at the site of injury or inflammation, so the area is more comfortable and easier to move.
In Inflammatory arthritis
Lefupro calms the inflammation driving joint pain and stiffness in arthritis, improving movement and protecting the joint from further damage.
In Gout
Lefupro relieves the intense pain and swelling of a gout attack, or lowers uric acid to prevent attacks, depending on the type you have been prescribed.
In Recovery after injury or surgery
Lefupro controls pain and swelling while tissues heal, which lets you move earlier and recover more comfortably.

How Lefupro 20 mg Tablet works

Leflunomide is a disease-modifying antirheumatic drug (DMARD). Its active metabolite inhibits dihydroorotate dehydrogenase, reducing pyrimidine synthesis and thereby suppressing proliferation and activity of activated T-lymphocytes, which decreases joint inflammation and damage.

How to take Lefupro 20 mg Tablet

Tablet for oral use. Take exactly as prescribed, usually once daily, with or without food, preferably at the same time each day. Do not stop abruptly without medical advice; regular blood tests are required during treatment.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can seriously suppress the bone marrow and damage the liver. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Lefupro 20 mg Tablet

Most side effects of Lefupro are mild and settle as the body gets used to the medicine. The ones reported most often are:

  • Diarrhoea
  • nausea
  • abdominal pain
  • headache
  • dizziness
  • rash
  • hair thinning/alopecia
  • elevated liver enzymes
  • hypertension
  • respiratory infections

Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Lefupro 20 mg Tablet

AlcoholUNSAFE
Do not drink alcohol while taking this medicine.
PregnancyUNSAFE
Not recommended in pregnancy. It may harm the developing baby, so tell your doctor at once if you are or might be pregnant.
Breast feedingUNSAFE
Lefupro 20 Tablets is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
DrivingCAUTION
May cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyCAUTION
Lefupro 20 Tablets should be used with caution in patients with kidney disease. Dose adjustment of Lefupro 20 Tablets may be needed. Please consult your doctor.
LiverUNSAFE
Lefupro 20 Tablets is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Warnings and precautions

Not recommended in pregnancy; causes severe birth defects—effective contraception is required during treatment and until drug is eliminated (may require cholestyramine/activated charcoal washout). Avoid breastfeeding. Risk of serious liver injury—do not use in severe hepatic impairment; avoid alcohol; monitor LFTs. Can cause bone marrow suppression/infections—monitor CBC; avoid live vaccines. Use caution in hypertension and lung disease (rare interstitial lung disease). Discuss washout before planned pregnancy (women and men) or before switching to another hepatotoxic/immunosuppressive drug.

Do not take Lefupro if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy.

Interactions with other medicines

Methotrexate and other hepatotoxic drugs (increased liver toxicity), warfarin (may alter INR), rifampicin (may increase active metabolite levels), cholestyramine/activated charcoal (markedly decreases levels; used for washout), live vaccines (reduced response/infection risk), other immunosuppressants (additive infection risk)

How to store Lefupro 20 mg Tablet

Store below 25°C in a dry place, protected from moisture and light. Keep in original pack and out of reach of children.

Quick tips for Lefupro 20 mg Tablet

  • Keep every monitoring blood test appointment.
  • Carry a note of the medicine and its schedule, especially for weekly dosing.

Manufacturer and class

Manufacturer:
BRINTON PHARMACEUTICALS
Therapeutic class:
Anti-rheumatic (DMARD)
Drug class:
Pyrimidine synthesis inhibitor (DMARD; dihydroorotate dehydrogenase inhibitor)

Substitutes for Lefupro 20 mg Tablet

Medicines with the same active ingredient (Leflunomide 20 mg). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Lefupro 20 mg Tablet
Lefra 10 TabletTorrent Pharmaceuticals Ltdtablet · 10`S₹17025% cheaper
Cleft 20 mg TabletSUN PHARMA 2tablet · 10`S₹228same price
Lefutoid 20 mg TabletLUPIN LABtablet · 10`S₹27521% more
Lefno 20 mg TabletIPCA LABORATORIES LTD`tablet · 10`S₹32041% more
Lefra 20 TabletTorrent Pharmaceuticals Ltdtablet · 10`S₹33246% more
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Lefupro 20 mg Tablet FAQs

What is Lefupro 20 mg Tablet used for?
Lefupro 20 mg Tablet is commonly used for Treatment of active rheumatoid arthritis; may also be used in psoriatic arthritis as prescribed. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Lefupro 20 mg Tablet?
Pain and swelling: Lefupro reduces pain and swelling at the site of injury or inflammation, so the area is more comfortable and easier to move. It is also used for inflammatory arthritis, gout, recovery after injury or surgery.
What is the salt in Lefupro 20 mg Tablet?
Lefupro 20 mg Tablet contains Leflunomide 20 mg. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Lefupro 20 mg Tablet?
Tablet for oral use. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Lefupro 20 mg Tablet work?
Leflunomide is a disease-modifying antirheumatic drug (DMARD).
Is Lefupro 20 mg Tablet a prescription medicine?
Yes. Lefupro 20 mg Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Lefupro 20 mg Tablet?
The side effects reported most often with Lefupro are Diarrhoea, nausea, abdominal pain, headache, dizziness. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Lefupro 20 mg Tablet be taken during pregnancy?
Lefupro 20 mg Tablet is not recommended in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Lefupro.
Can I drink alcohol while taking Lefupro 20 mg Tablet?
No. Do not drink alcohol while taking Lefupro 20 mg Tablet.
What if I miss a dose of Lefupro 20 mg Tablet?
Take it as soon as you remember.
Is Lefupro 20 mg Tablet habit forming?
No. Lefupro 20 mg Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Lefupro 20 mg Tablet?
Lefra 10 Tablet has the same active ingredient and strength and is listed from ₹170 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Lefupro 20 mg Tablet cost on PingMeDoc Pharmacy?
Lefupro 20 mg Tablet starts at ₹228 on PingMeDoc Pharmacy. Available in tablet 20 mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Lefupro 20 mg Tablet?
Lefupro 20 mg Tablet is manufactured by BRINTON PHARMACEUTICALS. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Lefupro 20 mg Tablet delivered?
Lefupro 20 mg Tablet is delivered across India from our licensed pharmacy. Orders placed before 2 pm ship the same day, later ones the next day, every day of the week. Chennai: next-day delivery by Porter, ₹99 (free above ₹1,499). Enter your pincode on the page to see the date it reaches you.

Lefupro 20 mg Tablet, Quick facts

Salt
Leflunomide 20 mg
Form
tablet
Price
₹228 (₹22.77 per tablet)
Prescription
Required (Rx)
Schedule
Schedule H
Brand
Brinton Pharmaceuticals Pvt Ltd
Manufacturer
BRINTON PHARMACEUTICALS
Therapeutic class
Anti-rheumatic (DMARD)
Drug class
Pyrimidine synthesis inhibitor (DMARD; dihydroorotate dehydrogenase inhibitor)
Habit forming
No
Variants
tablet 20 mg 10`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.

  1. Manufacturer labeling, established medical literature (DMARD/leflunomide monographs)
  2. CDSCO/Indian regulatory labeling standards
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Lefupro 20 mg Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.