Prescription requiredAntihypertensive / Antianginal

Metosux XL 25 — Side Effects & Warnings

Known side effects of Metosux XL 25 include Tiredness, dizziness, slow heart rate (bradycardia), low blood pressure, cold hands/feet, headache, nausea, sleep disturbances. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

Common Side Effects

Tiredness
dizziness
slow heart rate (bradycardia)
low blood pressure
cold hands/feet
headache
nausea
sleep disturbances

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Do not stop abruptly (risk of rebound hypertension/angina). Use with caution in asthma/COPD (may worsen bronchospasm), diabetes (may mask hypoglycaemia symptoms), thyroid disorders (may mask thyrotoxicosis), peripheral vascular disease, and in patients with low heart rate, heart block, or severe hypotension. In heart failure, initiate and titrate under medical supervision. Seek help if severe dizziness, fainting, wheeze, swelling, or very slow pulse occurs.

Drug Interactions

Metosux XL 25 may interact with the following:

Other antihypertensives (additive BP lowering)
calcium channel blockers like verapamil/diltiazem (risk of bradycardia/heart block)
digoxin (bradycardia)
antiarrhythmics like amiodarone (conduction disturbances)
clonidine (rebound hypertension if stopped improperly)
insulin/oral antidiabetics (masked hypoglycaemia)
NSAIDs (may reduce antihypertensive effect)
CYP2D6 inhibitors like fluoxetine/paroxetine/quinidine (increase metoprolol levels)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Use with caution / Consult doctor (may affect fetal growth; use only if clearly needed)

Alcohol Interaction

Use with caution (may increase dizziness and risk of low blood pressure)

Habit Forming

Storage

Store below 25°C in a dry place. Protect from moisture and light. Keep out of reach of children.

Metosux XL 25 — Safety Summary

Composition: Metoprolol succinate extended-release 25 mg
Prescription: Required (Rx)
Pregnancy: Use with caution / Consult doctor (may affect fetal growth; use only if clearly needed)
Alcohol: Use with caution (may increase dizziness and risk of low blood pressure)
Habit forming: No

Metosux XL 25 — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.