Prescription requiredNeuropathic pain agent (with vitamin supplement)

Pregal M 50 — Side Effects & Warnings

Known side effects of Pregal M 50 include Dizziness, drowsiness, fatigue, blurred vision, dry mouth, weight gain, peripheral edema (swelling), constipation, difficulty concentrating. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

Common Side Effects

Dizziness
drowsiness
fatigue
blurred vision
dry mouth
weight gain
peripheral edema (swelling)
constipation
difficulty concentrating

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

May cause dizziness and sleepiness—avoid driving or operating machinery until you know the effect. Use with caution in kidney disease (dose adjustment needed) and in elderly. Risk of swelling/edema and weight gain; caution in heart failure. Do not discontinue abruptly (may cause withdrawal symptoms). Rarely, mood changes or suicidal thoughts—seek medical help if they occur. Hypersensitivity reactions (rash, facial swelling) require urgent care.

Drug Interactions

Pregal M 50 may interact with the following:

Alcohol and other CNS depressants (increased drowsiness)
opioids (e.g.
tramadol
morphine) and benzodiazepines (additive sedation/respiratory depression risk)
antihistamines/sedatives
ACE inhibitors (may increase risk of angioedema)
medicines causing edema

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Use with caution / Consult doctor

Alcohol Interaction

Avoid

Habit Forming

Storage

Store at room temperature (below 25°C), protected from moisture and light. Keep in original blister pack and out of reach of children.

Pregal M 50 — Safety Summary

Composition: Pregabalin (50mg) + Mecobalamin (750mcg)
Prescription: Required (Rx)
Pregnancy: Use with caution / Consult doctor
Alcohol: Avoid
Habit forming: No

Pregal M 50 — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

Get help from a doctor

Consult a doctor

Discuss side effects with a qualified doctor online.

View all medicines

Full product details for Pregal M 50.

Lab tests

Book tests to monitor your health while on medication.

Sick leave certificate

Unwell and need rest? A doctor can issue a leave certificate online, from ₹499.

Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.