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Pregabalin 50 mg + Methylcobalamin (Mecobalamin) 750 mcg (tablet/capsule)
Neuropathic pain (e.g., diabetic neuropathy, post-herpetic neuralgia), nerve pain due to vitamin B12 deficiency, tingling/numbness in peripheral neuropathy
Pregabalin reduces abnormal nerve signaling by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the CNS, decreasing release of pain neurotransmitters. Methylcobalamin is an active form of vitamin B12 that supports myelin sheath repair and nerve regeneration, helping improve neuropathic symptoms.
Take by mouth as prescribed, usually once or twice daily; may be taken with or without food. Swallow whole with water; do not crush/chew. Do not stop suddenly—dose should be tapered under medical supervision.
Common side effects of PREGAL M 50 may include:
May cause dizziness and sleepiness—avoid driving or operating machinery until you know the effect. Use with caution in kidney disease (dose adjustment needed) and in elderly. Risk of swelling/edema and weight gain; caution in heart failure. Do not discontinue abruptly (may cause withdrawal symptoms). Rarely, mood changes or suicidal thoughts—seek medical help if they occur. Hypersensitivity reactions (rash, facial swelling) require urgent care.
