Prescription requiredAnti-asthmatic / COPD maintenance therapy

Seretide Accu 50/250MG. — Side Effects & Warnings

Known side effects of Seretide Accu 50/250MG. include Headache,throat irritation/hoarseness,cough,oral thrush (candidiasis),upper respiratory tract infection,tremor,palpitations, muscle cramps. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

Common Side Effects

Headache
throat irritation/hoarseness
cough
oral thrush (candidiasis)
upper respiratory tract infection
tremor
palpitations
muscle cramps

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Not for acute asthma/COPD attacks. Do not stop abruptly; step-down only on medical advice. Risk of pneumonia in COPD, and oral candidiasis—rinse mouth after use. Use with caution in heart disease, arrhythmias, hypertension, hyperthyroidism, diabetes, seizures, and in patients with low potassium. Seek urgent care if breathing worsens immediately after use (paradoxical bronchospasm). Long-term high-dose inhaled steroids may cause adrenal suppression, reduced bone mineral density, cataract/glaucoma—monitor if prolonged use.

Drug Interactions

Seretide Accu 50/250MG. may interact with the following:

Strong CYP3A4 inhibitors (e.g.
ritonavir
cobicistat
ketoconazole
itraconazole
clarithromycin) may increase systemic fluticasone/salmeterol effects; beta-blockers may reduce bronchodilation; other sympathomimetics increase cardiovascular effects; diuretics/xanthines/corticosteroids may increase risk of hypokalemia; MAO inhibitors/TCAs may potentiate beta-agonist effects.

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Consult doctor

Alcohol Interaction

No known interaction

Habit Forming

Storage

Store below 30°C in a cool, dry place; protect from moisture and direct heat. Keep device closed when not in use. Keep out of reach of children.

Seretide Accu 50/250MG. — Safety Summary

Composition: Salmeterol (as xinafoate) 50 mcg + Fluticasone propionate 250 mcg per inhalation (Accuhaler/Dry powder inhaler)
Prescription: Required (Rx)
Pregnancy: Consult doctor
Alcohol: No known interaction
Habit forming: No

Seretide Accu 50/250MG. — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.

Seretide Accu 50/250MG. — Side Effects & Warnings

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026