Prescription requiredAntidiabetic

Sitapep GM 1/50/500MG Tab — Side Effects & Warnings

Known side effects of Sitapep GM 1/50/500MG Tab include Hypoglycaemia, nausea, vomiting, diarrhoea, abdominal pain, loss of appetite, headache, dizziness, flatulence. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

Common Side Effects

Hypoglycaemia
nausea
vomiting
diarrhoea
abdominal pain
loss of appetite
headache
dizziness
flatulence

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Risk of hypoglycaemia (higher if meals are missed, with alcohol, or with other antidiabetics); metformin may rarely cause lactic acidosis—seek urgent care for rapid breathing, severe weakness, muscle pain, unusual sleepiness. Use caution in kidney or liver disease; dose adjustment/avoidance may be needed. Withhold metformin around iodinated contrast procedures and major surgery as advised. Not for type 1 diabetes or diabetic ketoacidosis. Elderly and malnourished patients are at higher hypoglycaemia risk.

Drug Interactions

Sitapep GM 1/50/500MG Tab may interact with the following:

Alcohol
insulin/other antidiabetics (additive hypoglycaemia)
corticosteroids (raise glucose)
diuretics and sympathomimetics (raise glucose)
ACE inhibitors (may enhance glucose-lowering)
fluoroquinolones (glycaemic disturbances)
beta-blockers (mask hypoglycaemia)
iodinated contrast media (metformin—lactic acidosis risk)
cationic drugs affecting renal excretion (e.g.
cimetidine)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Consult doctor

Alcohol Interaction

Avoid

Habit Forming

Storage

Store below 25°C in a cool, dry place. Protect from moisture and light. Keep out of reach of children.

Sitapep GM 1/50/500MG Tab — Safety Summary

Composition: Glimepiride 1 mg + Sitagliptin 50 mg + Metformin 500 mg (as Metformin Hydrochloride)
Prescription: Required (Rx)
Pregnancy: Consult doctor
Alcohol: Avoid
Habit forming: No

Sitapep GM 1/50/500MG Tab — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.