Prescription requiredThyroid hormone replacement

Thyroup 25 — Side Effects & Warnings

Known side effects of Thyroup 25 include Palpitations,fast heartbeat,anxiety,irritability,tremor,headache,insomnia,heat intolerance,increased sweating,weight loss,diarrhoea,nausea,menstrual irregularities. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

Common Side Effects

Palpitations
fast heartbeat
anxiety
irritability
tremor
headache
insomnia
heat intolerance
increased sweating
weight loss
diarrhoea
nausea
menstrual irregularities

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Use only under medical supervision with periodic TSH monitoring. Overdose/over-replacement may cause symptoms of hyperthyroidism and increase risk of arrhythmias, angina or osteoporosis. Use caution in elderly and in patients with coronary artery disease, heart failure, arrhythmias, hypertension, adrenal insufficiency or uncontrolled thyrotoxicosis (contraindicated). Correct adrenal insufficiency before starting. Not for weight loss; high doses can be dangerous.

Drug Interactions

Thyroup 25 may interact with the following:

Reduced absorption with calcium salts
iron salts
aluminium/magnesium antacids
sucralfate
cholestyramine/colestipol
sevelamer; increased requirements with rifampicin
carbamazepine
phenytoin
phenobarbital
sertraline; potentiates warfarin effect (INR monitoring); may alter insulin/oral antidiabetic needs; caution with digoxin (effect may decrease as thyroid status normalizes).

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Generally safe (often required); dose adjustment and TSH monitoring needed during pregnancy

Alcohol Interaction

Use with caution (no direct interaction; alcohol may worsen symptoms or adherence; avoid excessive intake)

Habit Forming

Storage

Store below 25°C, protected from light and moisture. Keep in original blister/strip, tightly closed. Keep out of reach of children.

Thyroup 25 — Safety Summary

Composition: Thyroxine (25mcg)
Prescription: Required (Rx)
Pregnancy: Generally safe (often required); dose adjustment and TSH monitoring needed during pregnancy
Alcohol: Use with caution (no direct interaction; alcohol may worsen symptoms or adherence; avoid excessive intake)
Habit forming: No

Thyroup 25 — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.

Thyroup 25 — Side Effects & Warnings

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026