
Ab Flo Caps
Lupin Lab - Capsule - 15 S
Prescription required
Thyroxine (25mcg)
Thyroup 25 is used for treatment of hypothyroidism (underactive thyroid), thyroid hormone replacement after thyroidectomy or radioactive iodine therapy, management of goitre due to thyroid hormone deficiency.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026
Thyroup 25 contains Thyroxine (25mcg). It belongs to the Thyroid hormone (synthetic T4) class of medicines.
Levothyroxine is a synthetic form of thyroxine (T4), a natural thyroid hormone. It is converted to triiodothyronine (T3) in the body and restores normal thyroid hormone levels, helping regulate metabolism, energy and growth.
Tablet for oral use. Take once daily on an empty stomach, preferably in the morning 30–60 minutes before breakfast, with water. Take at the same time each day; avoid taking with calcium/iron/antacids—keep a 4-hour gap. Dose is individualized based on TSH and clinical response; do not stop abruptly without medical advice.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Thyroup 25 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Taking more Thyroup than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.
Most side effects of Thyroup are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Generally safe (often required); dose adjustment and TSH monitoring needed during pregnancy |
|---|---|
| Breastfeeding | Breast feeding SAFE IF PRESCRIBED |
| Alcohol | Use with caution (no direct interaction; alcohol may worsen symptoms or adherence; avoid excessive intake) |
| Driving | Driving SAFE |
| Kidney | Kidney SAFE IF PRESCRIBED |
| Liver | Liver CONSULT YOUR DOCTOR |
| Habit forming | No |
Use only under medical supervision with periodic TSH monitoring. Overdose/over-replacement may cause symptoms of hyperthyroidism and increase risk of arrhythmias, angina or osteoporosis. Use caution in elderly and in patients with coronary artery disease, heart failure, arrhythmias, hypertension, adrenal insufficiency or uncontrolled thyrotoxicosis (contraindicated). Correct adrenal insufficiency before starting. Not for weight loss; high doses can be dangerous.
Reduced absorption with calcium salts,iron salts,aluminium/magnesium antacids,sucralfate,cholestyramine/colestipol,sevelamer; increased requirements with rifampicin,carbamazepine,phenytoin,phenobarbital,sertraline; potentiates warfarin effect (INR monitoring); may alter insulin/oral antidiabetic needs; caution with digoxin (effect may decrease as thyroid status normalizes).
Store below 25°C, protected from light and moisture. Keep in original blister/strip, tightly closed. Keep out of reach of children.
Thyroup 25 Tablet should be taken on an empty stomach (ideally, first thing in the morning). No food, milk, or tea should be taken 1 hour before and 2 hours after taking this medicine. It may take 6 to 8 weeks to get the full effect. For most people, Thyroup 25 Tablet can be a lifelong medication. Do not discontinue it without discussing your doctor. Inform your doctor if you have diarrhea, nervousness, irritability, sleep disturbances, shaking hands, or chest pain. Your doctor may adjust your dose. Leave a gap of at least 4 hours before taking any antacids, calcium or iron supplements, and multivitamins, as these may interfere with the effect of the medicine. Get your hormone levels checked regularly and inform your doctor if you notice a significant change in your body weight. The dose may need to be adjusted. Inform your doctor before changing the brand of Thyroup 25 Tablet as all brands may not have the same effect.
Medicines with the same active ingredient (Thyroxine (25mcg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Thyroup 25 |
|---|---|---|---|
| Lethyrox 25Intas Pharmaceuticals Ltd | 120`S | ₹169 | 9% cheaper |
| Thyroup 12.5 mg TabletLUPIN LAB | tablet · 120`S | ₹190 | 2% more |

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The information on Thyroup 25 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.