Prescription requiredAntidiabetic

ZINODAP M5/1000 SR — Side Effects & Warnings

Known side effects of ZINODAP M5/1000 SR include Nausea, diarrhoea, abdominal discomfort, decreased appetite, headache, increased urination, genital fungal infection, urinary tract infection, dizziness. Not everyone experiences these side effects.

Common Side Effects

Nausea
diarrhoea
abdominal discomfort
decreased appetite
headache
increased urination
genital fungal infection
urinary tract infection
dizziness

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Not for type 1 diabetes. Risk of lactic acidosis with metformin (higher risk in severe kidney impairment, dehydration, sepsis, hypoxia, alcohol abuse); stop and seek care for rapid breathing, severe weakness, abdominal pain. Dapagliflozin may cause genital mycotic infections, UTIs, volume depletion/low BP, and rarely ketoacidosis (can occur with normal sugars); stop and seek care for nausea, vomiting, abdominal pain, rapid breathing. Assess kidney function before and periodically; dose/use may be restricted in reduced eGFR. Withhold before major surgery and during acute illness or prolonged fasting; restart when stable and eating. Use caution in elderly, on diuretics, or with low BP. Consider vitamin B12 monitoring with long-term metformin. Inform doctor before iodinated contrast procedures; may need temporary discontinuation.

Drug Interactions

ZINODAP M5/1000 SR may interact with the following:

Insulin and sulfonylureas (increased hypoglycaemia risk)
diuretics (increased dehydration/low BP risk)
ACE inhibitors/ARBs (may enhance BP lowering)
NSAIDs and nephrotoxic drugs (worsen renal function affecting metformin safety)
alcohol (increases lactic acidosis risk)
iodinated contrast media (risk of lactic acidosis—temporary stop)
cationic drugs affecting renal tubular secretion e.g. cimetidine (may increase metformin levels)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Not recommended; consult doctor (generally avoid SGLT2 inhibitors in 2nd/3rd trimester; use only if clearly needed)

Alcohol Interaction

Avoid (increases risk of lactic acidosis and dehydration)

Habit Forming

Storage

Store below 25°C in a dry place, protected from moisture and light. Keep in original blister pack and out of reach of children.

ZINODAP M5/1000 SR — Safety Summary

Composition: Dapagliflozin 10 mg + Metformin (as Metformin Hydrochloride) 1000 mg (Sustained Release)
Prescription: Required (Rx)
Pregnancy: Not recommended; consult doctor (generally avoid SGLT2 inhibitors in 2nd/3rd trimester; use only if clearly needed)
Alcohol: Avoid (increases risk of lactic acidosis and dehydration)
Habit forming: No

ZINODAP M5/1000 SR — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.