
Decdan 0.5 Tablet
Wockhardt Ltd - Tablet - 10 Tablet
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Dapagliflozin 10 mg + Metformin (as Metformin Hydrochloride) 1000 mg (Sustained Release)
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Zinodap M5/1000 SR is used for type 2 diabetes mellitus: to improve glycaemic control in adults as an adjunct to diet and exercise, when dual therapy with metformin and an SGLT2 inhibitor is appropriate.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Zinodap M5/1000 SR contains Dapagliflozin 10 mg + Metformin (as Metformin Hydrochloride) 1000 mg (Sustained Release). It belongs to the SGLT2 inhibitor + Biguanide class of medicines.
Dapagliflozin is an SGLT2 inhibitor that reduces glucose reabsorption in the kidneys, increasing urinary glucose excretion. Metformin decreases hepatic glucose production and improves insulin sensitivity; the SR form releases drug slowly to improve GI tolerability and provide prolonged effect.
Oral tablet (SR). Take exactly as prescribed, usually once daily with a meal (preferably with/after the main meal) to reduce stomach upset. Swallow whole; do not crush, chew or break. Maintain adequate hydration.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause dehydration and a fall in blood pressure. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Zinodap M5/1000 SR are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Not recommended; consult doctor (generally avoid SGLT2 inhibitors in 2nd/3rd trimester; use only if clearly needed) |
|---|---|
| Breastfeeding | Not recommended while breastfeeding. |
| Alcohol | Avoid (increases risk of lactic acidosis and dehydration) |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Not for type 1 diabetes. Risk of lactic acidosis with metformin (higher risk in severe kidney impairment, dehydration, sepsis, hypoxia, alcohol abuse); stop and seek care for rapid breathing, severe weakness, abdominal pain. Dapagliflozin may cause genital mycotic infections, UTIs, volume depletion/low BP, and rarely ketoacidosis (can occur with normal sugars); stop and seek care for nausea, vomiting, abdominal pain, rapid breathing. Assess kidney function before and periodically; dose/use may be restricted in reduced eGFR. Withhold before major surgery and during acute illness or prolonged fasting; restart when stable and eating. Use caution in elderly, on diuretics, or with low BP. Consider vitamin B12 monitoring with long-term metformin. Inform doctor before iodinated contrast procedures; may need temporary discontinuation.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.
Insulin and sulfonylureas (increased hypoglycaemia risk), diuretics (increased dehydration/low BP risk), ACE inhibitors/ARBs (may enhance BP lowering), NSAIDs and nephrotoxic drugs (worsen renal function affecting metformin safety), alcohol (increases lactic acidosis risk), iodinated contrast media (risk of lactic acidosis—temporary stop), cationic drugs affecting renal tubular secretion e.g. cimetidine (may increase metformin levels)
Store below 25°C in a dry place, protected from moisture and light. Keep in original blister pack and out of reach of children.
Take it in the morning so the extra urine does not disturb your sleep. Keep up your fluid intake and maintain genital hygiene. Tell any doctor treating you for an acute illness that you take this medicine. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

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Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.