Prescription requiredAntidiabetic

Zomelis Met 50/500 Tablet — Side Effects & Warnings

Known side effects of Zomelis Met 50/500 Tablet include Nausea, vomiting, diarrhoea, abdominal pain, loss of appetite, metallic taste, headache, dizziness, upper respiratory tract infection, hypoglycaemia (especially with insulin/sulfonylureas), rash. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026

Common Side Effects

Nausea
vomiting
diarrhoea
abdominal pain
loss of appetite
metallic taste
headache
dizziness
upper respiratory tract infection
hypoglycaemia (especially with insulin/sulfonylureas)
rash

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Prescription (Schedule H) medicine. Risk of lactic acidosis with metformin—seek urgent care for fast breathing, severe weakness, muscle pain, unusual sleepiness, or abdominal discomfort; higher risk in kidney impairment, dehydration, severe infection, hypoxia, heavy alcohol use, and elderly. Monitor renal function before and during therapy; not recommended in severe renal impairment. Temporarily stop around iodinated contrast procedures and major surgery as advised. Sitagliptin may rarely cause pancreatitis—seek medical help for severe persistent abdominal pain. Use caution in heart failure history and in patients prone to hypoglycaemia when combined with insulin or sulfonylureas.

Drug Interactions

Zomelis Met 50/500 Tablet may interact with the following:

Alcohol (increases lactic acidosis risk)
iodinated contrast media
carbonic anhydrase inhibitors (e.g.
topiramate
acetazolamide)
cimetidine
ranolazine
dolutegravir
vandetanib
drugs that raise blood glucose (corticosteroids
thiazide/loop diuretics)
insulin and sulfonylureas (increased hypoglycaemia risk)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Consult doctor

Alcohol Interaction

Avoid

Habit Forming

Storage

Store below 25°C in a cool, dry place. Protect from moisture and light. Keep in original strip and out of reach of children.

Zomelis Met 50/500 Tablet — Safety Summary

Composition: Metformin (500mg) + Vildagliptin (50mg)
Prescription: Required (Rx)
Pregnancy: Consult doctor
Alcohol: Avoid
Habit forming: No

Zomelis Met 50/500 Tablet — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

Get help from a doctor

Consult a doctor

Discuss side effects with a qualified doctor online.

View all medicines

Full product details for Zomelis Met 50/500 Tablet.

Lab tests

Book tests to monitor your health while on medication.

Sick leave certificate

Unwell and need rest? A doctor can issue a leave certificate online, from ₹499.

Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.

Zomelis Met 50/500 Tablet — Side Effects & Warnings

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026