Prescription requiredAntidiabetic

Zomelis Met 50/850MG Tab — Side Effects & Warnings

Known side effects of Zomelis Met 50/850MG Tab include Nausea, vomiting, diarrhoea, abdominal pain, loss of appetite, metallic taste, headache, upper respiratory tract infection, nasopharyngitis. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026

Common Side Effects

Nausea
vomiting
diarrhoea
abdominal pain
loss of appetite
metallic taste
headache
upper respiratory tract infection
nasopharyngitis

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Prescription only. Risk of lactic acidosis with metformin (medical emergency): higher risk in kidney impairment, dehydration, severe infection, hypoxia, heart failure, liver disease, or excess alcohol; stop and seek help if fast breathing, severe weakness, muscle pain, abdominal pain, or drowsiness occur. Assess renal function before and during therapy; dose adjustment/avoid in significant renal impairment. Temporarily stop metformin before iodinated contrast procedures and major surgery as advised. Sitagliptin: rare pancreatitis and severe joint pain; stop and consult if severe persistent abdominal pain. Monitor for hypoglycaemia if used with insulin/sulfonylureas.

Drug Interactions

Zomelis Met 50/850MG Tab may interact with the following:

Alcohol (increases lactic acidosis risk)
iodinated contrast media
carbonic anhydrase inhibitors (e.g.
topiramate
acetazolamide)
cationic drugs that reduce metformin clearance (e.g.
cimetidine)
insulin/sulfonylureas (increased hypoglycaemia risk)
digoxin (sitagliptin may slightly increase levels)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Consult doctor

Alcohol Interaction

Avoid

Habit Forming

Storage

Store below 25°C, protected from moisture and light. Keep in original blister pack and out of reach of children.

Zomelis Met 50/850MG Tab — Safety Summary

Composition: Sitagliptin 50 mg + Metformin Hydrochloride 850 mg (as immediate-release tablet)
Prescription: Required (Rx)
Pregnancy: Consult doctor
Alcohol: Avoid
Habit forming: No

Zomelis Met 50/850MG Tab — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.

Zomelis Met 50/850MG Tab — Side Effects & Warnings

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026