Prescription requiredAntidiabetic

Zoryl Ms Ir 2/1000 — Uses, Dosage & Benefits

Zoryl Ms Ir 2/1000 is used for Type 2 diabetes mellitus: to improve blood glucose control in adults when diet and exercise alone are not sufficient, or when dual therapy with sulfonylurea and metformin is appropriate.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

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Active Ingredient / Composition

Sitagliptin (50mg) + Glimepiride (2mg) + Metformin (1000mg)

What is Zoryl Ms Ir 2/1000 used for?

Type 2 diabetes mellitus: to improve blood glucose control in adults when diet and exercise alone are not sufficient
or when dual therapy with sulfonylurea and metformin is appropriate

How Zoryl Ms Ir 2/1000 Works

Glimepiride (a sulfonylurea) stimulates pancreatic beta cells to release insulin and improves peripheral glucose utilization. Metformin (a biguanide) decreases hepatic glucose production and improves insulin sensitivity, reducing intestinal glucose absorption.

Dosage & Directions

Oral tablet. Take exactly as prescribed, usually with food to reduce stomach upset (commonly with breakfast or the first main meal). Swallow with water; do not skip meals as it may increase risk of low blood sugar. Dose is individualized based on blood glucose/HbA1c and kidney function.

Always follow your doctor's prescription. Do not self-medicate.

Key Benefits

Lowers fasting and post-meal blood glucose
Improves insulin sensitivity and reduces liver glucose production
Helps achieve HbA1c targets with dual therapy
Convenient combination may reduce pill burden

Pregnancy

Not recommended; consult doctor (insulin is generally preferred in pregnancy)

Alcohol Interaction

Avoid

Zoryl Ms Ir 2/1000 — Quick Facts

Composition: Sitagliptin (50mg) + Glimepiride (2mg) + Metformin (1000mg)
Therapeutic class: Antidiabetic
Drug class: Sulfonylurea + Biguanide
Prescription: Required (Rx)
Price: ₹155
Habit forming: No
Storage: Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

Zoryl Ms Ir 2/1000 — Usage FAQs

How should I take this medicine?

Follow the dosage prescribed by your doctor. Do not alter the dose without medical advice.

Can I take this medicine without a prescription?

Prescription-required medicines need a valid Rx. OTC medicines can be purchased directly.

What if I miss a dose?

Take the missed dose as soon as you remember, unless it is close to your next scheduled dose. Do not double the dose.

How long does it take to show effect?

The time to show effect varies by medicine and condition. Consult your doctor for specific timelines.

Zoryl Ms Ir 2/1000 — Uses, Dosage & Benefits

Active Ingredient / Composition

What is Zoryl Ms Ir 2/1000 used for?

How Zoryl Ms Ir 2/1000 Works

Dosage & Directions

Key Benefits

Pregnancy

Alcohol Interaction

Zoryl Ms Ir 2/1000 — Quick Facts

Zoryl Ms Ir 2/1000 — Usage FAQs

More from PingMeDoc™

Safety disclaimer

Zoryl Ms Ir 2/1000 — Uses, Dosage & Benefits

Active Ingredient / Composition

What is Zoryl Ms Ir 2/1000 used for?

How Zoryl Ms Ir 2/1000 Works

Dosage & Directions

Key Benefits

Pregnancy

Alcohol Interaction

Zoryl Ms Ir 2/1000 — Quick Facts

Zoryl Ms Ir 2/1000 — Usage FAQs

More from PingMeDoc™

Safety disclaimer