Prescription requiredNasal decongestant

Zylo Nasal Drops — Side Effects & Warnings

Known side effects of Zylo Nasal Drops include Nasal burning or stinging, dryness/irritation of nose or throat, sneezing, headache, nausea, palpitations, increased blood pressure, rebound congestion with prolonged use. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026

Common Side Effects

Nasal burning or stinging
dryness/irritation of nose or throat
sneezing
headache
nausea
palpitations
increased blood pressure
rebound congestion with prolonged use

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Do not use for more than 3-5 days (risk of rhinitis medicamentosa/rebound congestion). Use with caution in hypertension, heart disease, hyperthyroidism, diabetes, enlarged prostate, glaucoma. Avoid in atrophic rhinitis and after certain nasal surgeries unless advised. Not recommended for young children unless prescribed. Seek medical help if symptoms persist, worsen, or if severe headache, chest pain, fast heartbeat occurs.

Drug Interactions

Zylo Nasal Drops may interact with the following:

MAO inhibitors (and within 14 days of stopping)
tricyclic antidepressants
other sympathomimetics/decongestants; may increase risk of hypertension/arrhythmias

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Consult doctor (use with caution; short-term use only if clearly needed)

Alcohol Interaction

No known interaction

Habit Forming

Storage

Store below 25°C, protected from light and moisture. Keep container tightly closed; do not freeze. Keep out of reach of children.

Zylo Nasal Drops — Safety Summary

Composition: Xylometazoline hydrochloride 0.1% w/v (nasal drops)
Prescription: Required (Rx)
Pregnancy: Consult doctor (use with caution; short-term use only if clearly needed)
Alcohol: No known interaction
Habit forming: No

Zylo Nasal Drops — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.

Zylo Nasal Drops — Side Effects & Warnings

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026