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OTC · No prescriptionNulife Pharmaceuticals`Nasal decongestant

Zylo Nasal Drops

Xylometazoline hydrochloride 0.1% w/v (nasal drops)

Currently out of stock

Same composition, in stock now. Check with your doctor or pharmacist before you switch.

  • Otrivin Advance Adult Nasal Spray₹218View

Zylo Nasal Drops is used for relief of nasal congestion due to common cold, allergic rhinitis (hay fever), sinusitis; helps open blocked nose and relieve stuffiness.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Xylometazoline hydrochloride 0.1% w/v (nasal drops)
Available variants: drop 0.1%w/v 10ML
Best price: ₹51 (₹5.11 per ml)
MRP: ₹54
Prescription: Not required
Manufacturer: NULIFE PHARMACEUTICALS`

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Zylo Nasal Drops

Zylo Nasal Drops contains Xylometazoline hydrochloride 0.1% w/v (nasal drops). It belongs to the Imidazoline derivative; alpha-adrenergic agonist (topical nasal sympathomimetic) class of medicines.

Uses of Zylo Nasal Drops

  • Relief of nasal congestion due to common cold
  • allergic rhinitis (hay fever)
  • sinusitis; helps open blocked nose and relieve stuffiness

Key benefits

  • Provides fast relief from blocked nose
  • Reduces nasal mucosal swelling
  • Improves breathing through the nose
  • Helps relieve congestion in cold/allergy/sinusitis

How Zylo Nasal Drops works

Xylometazoline is a topical nasal decongestant (alpha-adrenergic agonist). It constricts dilated blood vessels in the nasal mucosa, reducing swelling and mucus formation and improving airflow.

How to take Zylo Nasal Drops

For intranasal use only. Instill the prescribed number of drops into each nostril as directed, usually 2-3 times daily. Blow nose gently before use; keep head tilted back while instilling. Do not use continuously for more than 3-5 days to avoid rebound congestion; follow doctor’s advice for children.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.

If you take too much

An overdose of this medicine may cause a racing heart, restlessness and a rise in blood pressure if swallowed. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Zylo Nasal Drops

Most side effects of Zylo Nasal are mild and settle as the body adjusts. Reported side effects include:

  • Nasal burning or stinging
  • dryness/irritation of nose or throat
  • sneezing
  • headache
  • nausea
  • palpitations
  • increased blood pressure
  • rebound congestion with prolonged use

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zylo Nasal Drops

PregnancyConsult doctor (use with caution; short-term use only if clearly needed)
BreastfeedingConsult your doctor before using this while breastfeeding.
AlcoholNo known interaction
DrivingNot expected to affect your ability to drive.
KidneyNo dose change is usually needed in kidney disease.
LiverNo dose change is usually needed in liver disease.
Habit formingNo

Warnings and precautions

Do not use for more than 3-5 days (risk of rhinitis medicamentosa/rebound congestion). Use with caution in hypertension, heart disease, hyperthyroidism, diabetes, enlarged prostate, glaucoma. Avoid in atrophic rhinitis and after certain nasal surgeries unless advised. Not recommended for young children unless prescribed. Seek medical help if symptoms persist, worsen, or if severe headache, chest pain, fast heartbeat occurs.

Do not take Zylo Nasal if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Decongestant sprays are not suitable for very young children without medical advice.

Interactions with other medicines

MAO inhibitors (and within 14 days of stopping), tricyclic antidepressants, other sympathomimetics/decongestants; may increase risk of hypertension/arrhythmias

How to store Zylo Nasal Drops

Store below 25°C, protected from light and moisture. Keep container tightly closed; do not freeze. Keep out of reach of children.

Expert advice for Zylo Nasal Drops

Blow your nose gently before using the spray. Steam inhalation and saline rinses help without any rebound risk.

Manufacturer and class

Manufacturer:
NULIFE PHARMACEUTICALS`
Therapeutic class:
Nasal decongestant
Drug class:
Imidazoline derivative; alpha-adrenergic agonist (topical nasal sympathomimetic)

Substitutes for Zylo Nasal Drops

Medicines with the same active ingredient (Xylometazoline hydrochloride 0.1% w/v (nasal drops)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Zylo Nasal Drops
Otrivin Advance Adult Nasal SprayGlaxoSmithKline Consumer Pvt Ltdspray · 10 Gm₹218328% more
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Zylo Nasal Drops FAQs

What is Zylo Nasal Drops used for?
Zylo Nasal Drops is commonly used for Relief of nasal congestion due to common cold, allergic rhinitis (hay fever), sinusitis; helps open blocked nose and relieve stuffiness. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Zylo Nasal Drops?
Zylo Nasal Drops contains Xylometazoline hydrochloride 0.1% w/v (nasal drops). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Zylo Nasal Drops?
For intranasal use only. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Zylo Nasal Drops work?
Xylometazoline is a topical nasal decongestant (alpha-adrenergic agonist).
Is Zylo Nasal Drops a prescription medicine?
No. Zylo Nasal Drops is available over the counter (OTC), no prescription is required. However, it is always safer to consult a doctor or pharmacist before use.
What are the common side effects of Zylo Nasal Drops?
The side effects reported most often with Zylo Nasal are Nasal burning or stinging, dryness/irritation of nose or throat, sneezing, headache, nausea. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Zylo Nasal Drops be taken during pregnancy?
Consult doctor (use with caution; short-term use only if clearly needed) Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Zylo Nasal.
Can I drink alcohol while taking Zylo Nasal Drops?
No known interaction
What if I miss a dose of Zylo Nasal Drops?
Apply it as soon as you remember.
Is Zylo Nasal Drops habit forming?
No. Zylo Nasal Drops is not known to be habit forming when taken as prescribed.
How much does Zylo Nasal Drops cost on PingMeDoc Pharmacy?
Zylo Nasal Drops starts at ₹51 (MRP ₹54) on PingMeDoc Pharmacy. Available in drop 0.1%w/v 10ML. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Zylo Nasal Drops?
Zylo Nasal Drops is manufactured by NULIFE PHARMACEUTICALS`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Zylo Nasal Drops delivered?
Zylo Nasal Drops is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Zylo Nasal Drops, Quick facts

Salt
Xylometazoline hydrochloride 0.1% w/v (nasal drops)
Form
drop
Best price
₹51 (₹5.11 per ml)
MRP
₹54
Prescription
Not required (OTC)
Brand
NULIFE PHARMACEUTICALS`
Manufacturer
NULIFE PHARMACEUTICALS`
Therapeutic class
Nasal decongestant
Drug class
Imidazoline derivative; alpha-adrenergic agonist (topical nasal sympathomimetic)
Habit forming
No
Variants
drop 0.1%w/v 10ML
Delivery
Standard across India

References

The information on Zylo Nasal Drops is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Manufacturer labeling/standard drug monographs, established medical literature
  2. Indian pharmacy practice references
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Zylo Nasal Drops.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.