Distributor inventory | Tablet

Treatment of type 2 diabetes mellitus in adults when blood sugar is not adequately controlled with diet, exercise and/or other antidiabetic medicines; helps control fasting and post‑meal glucose and improve insulin sensitivity.

Glimepiride (a sulfonylurea) increases insulin release from pancreatic beta cells. Metformin reduces hepatic glucose production and improves peripheral insulin sensitivity. Pioglitazone (a thiazolidinedione) improves insulin sensitivity in muscle and adipose tissue via PPAR‑γ activation.

Oral tablet; take exactly as prescribed. Usually taken once daily with or immediately after food (often with breakfast) to reduce stomach upset and risk of low sugar; swallow whole (do not crush/chew if modified/extended release). Monitor blood glucose regularly.

Hypoglycaemia, dizziness, headache, nausea, diarrhoea, abdominal pain, metallic taste, weight gain, oedema (swelling), fatigue

Prescription only. Risk of hypoglycaemia (especially if meals are skipped, alcohol use, or with other antidiabetics); carry glucose. Metformin: risk of lactic acidosis—avoid in severe kidney impairment, severe liver disease, dehydration, sepsis, hypoxia; stop temporarily around major surgery or iodinated contrast as advised. Pioglitazone: may cause fluid retention/worsen heart failure; avoid in NYHA class III/IV heart failure; monitor for weight gain/oedema. Possible risk of fractures and rare bladder cancer—avoid in active bladder cancer/ unexplained hematuria. Monitor kidney function, liver enzymes, and blood glucose/HbA1c. Not for type 1 diabetes or diabetic ketoacidosis.

Alcohol (increases hypoglycaemia and lactic acidosis risk), insulin or other sulfonylureas/meglitinides (hypoglycaemia), diuretics/corticosteroids/thyroid hormones (may raise glucose), beta-blockers (mask hypoglycaemia symptoms), ACE inhibitors (may enhance glucose-lowering), iodinated contrast media (lactic acidosis risk—hold metformin as advised), cimetidine (raises metformin levels), rifampicin (may reduce pioglitazone effect), gemfibrozil (increases pioglitazone levels)

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister/strip and out of reach of children.

Glimestar-PM 3 Forte Tablet, Glimy-MP 3 Tablet, Glimiprex-MP 3 Tablet, Glycomet-GP 3 Tablet, Zoryl-MP 3 Tablet