Drug ClassSulfonylurea + Biguanide + Thiazolidinedione (TZD)
PrescriptionRequired (Rx)
Habit FormingNo
Overview
Distributor inventory | Tablet
Uses & Benefits
Treatment of type 2 diabetes mellitus in adults when blood sugar is not adequately controlled with diet, exercise and/or other antidiabetic medicines; helps control fasting and post‑meal glucose and improve insulin sensitivity.
How It Works
Glimepiride (a sulfonylurea) increases insulin release from pancreatic beta cells. Metformin reduces hepatic glucose production and improves peripheral insulin sensitivity. Pioglitazone (a thiazolidinedione) improves insulin sensitivity in muscle and adipose tissue via PPAR‑γ activation.
Directions for Use
Oral tablet; take exactly as prescribed. Usually taken once daily with or immediately after food (often with breakfast) to reduce stomach upset and risk of low sugar; swallow whole (do not crush/chew if modified/extended release). Monitor blood glucose regularly.
Prescription only. Risk of hypoglycaemia (especially if meals are skipped, alcohol use, or with other antidiabetics); carry glucose. Metformin: risk of lactic acidosis—avoid in severe kidney impairment, severe liver disease, dehydration, sepsis, hypoxia; stop temporarily around major surgery or iodinated contrast as advised. Pioglitazone: may cause fluid retention/worsen heart failure; avoid in NYHA class III/IV heart failure; monitor for weight gain/oedema. Possible risk of fractures and rare bladder cancer—avoid in active bladder cancer/ unexplained hematuria. Monitor kidney function, liver enzymes, and blood glucose/HbA1c. Not for type 1 diabetes or diabetic ketoacidosis.
ManufacturerTORRENT PHARMACEUTICALS
BrandTorrent Pharmaceuticals Ltd
Drug Interactions
Alcohol (increases hypoglycaemia and lactic acidosis risk), insulin or other sulfonylureas/meglitinides (hypoglycaemia), diuretics/corticosteroids/thyroid hormones (may raise glucose), beta-blockers (mask hypoglycaemia symptoms), ACE inhibitors (may enhance glucose-lowering), iodinated contrast media (lactic acidosis risk—hold metformin as advised), cimetidine (raises metformin levels), rifampicin (may reduce pioglitazone effect), gemfibrozil (increases pioglitazone levels)
Storage Instructions
Store below 25°C in a dry place, protected from light and moisture. Keep in original blister/strip and out of reach of children.
Treatment of type 2 diabetes mellitus in adults when blood sugar is not adequately controlled with diet, exercise and/or other antidiabetic medicines; helps control fasting and post‑meal glucose and improve insulin sensitivity.
Glimepiride (a sulfonylurea) increases insulin release from pancreatic beta cells. Metformin reduces hepatic glucose production and improves peripheral insulin sensitivity. Pioglitazone (a thiazolidinedione) improves insulin sensitivity in muscle and adipose tissue via PPAR‑γ activation.
How should I use this medicine?
Oral tablet; take exactly as prescribed. Usually taken once daily with or immediately after food (often with breakfast) to reduce stomach upset and risk of low sugar; swallow whole (do not crush/chew if modified/extended release). Monitor blood glucose regularly.
How should I store this medicine?
Store below 25°C in a dry place, protected from light and moisture. Keep in original blister/strip and out of reach of children.
Do I need a prescription for this product?
Yes, this product requires a valid prescription (Rx). Upload it during checkout when prompted.
Can prices or availability change?
Yes. Prices and availability can change based on inventory and serviceability. The latest details are shown at checkout.
How do I place an order?
Select a variant, add to cart, enter delivery address, upload prescription if required, and pay securely.
Manufacturer & Brand
Brand:Torrent Pharmaceuticals Ltd
Manufacturer:TORRENT PHARMACEUTICALS
HSN Code:30049099
Alternatives
Alternatives are suggested by pharmacists after reviewing your order and prescription.
Disclaimer: Product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalized guidance.
Sources: Manufacturer labeling/pack information, established medical literature for glimepiride-metformin-pioglitazone, Indian prescribing information and safety guidance