Diaclide 60MR Tab

Tablet

Treatment of type 2 diabetes mellitus in adults when diet, exercise and weight reduction alone are insufficient; helps control blood glucose levels.

Gliclazide is a sulfonylurea antidiabetic that stimulates insulin release from pancreatic beta cells by closing ATP-sensitive potassium channels. The modified-release formulation provides a prolonged effect to help maintain stable blood glucose control.

Oral tablet (modified release). Typically taken once daily with breakfast; swallow whole with water—do not crush, chew, or split. Use exactly as prescribed and monitor blood glucose regularly; avoid skipping meals.

Hypoglycaemia, dizziness, headache, nausea, abdominal pain, diarrhoea, constipation, weight gain, skin rash, itching

Risk of hypoglycaemia (higher with missed meals, heavy exercise, alcohol, elderly, renal/hepatic impairment); educate on recognizing and treating low sugar. Use with caution in kidney or liver disease; dose adjustment/alternative may be needed. Not recommended in type 1 diabetes, diabetic ketoacidosis, or severe infections/major surgery (may need insulin). Inform doctor about G6PD deficiency (risk of haemolysis). Avoid driving/operating machinery if symptoms of hypoglycaemia occur.

Other antidiabetics/insulin (increased hypoglycaemia risk), alcohol (may cause hypoglycaemia), beta-blockers (may mask hypoglycaemia symptoms), fluconazole/miconazole (increase gliclazide levels), macrolide antibiotics (e.g., clarithromycin), NSAIDs/salicylates (enhance hypoglycaemia), corticosteroids/thiazide diuretics (increase blood glucose), rifampicin (reduces effect), warfarin (may alter anticoagulant effect)

Store below 25°C in a dry place, protected from moisture and light. Keep in original blister pack and out of reach of children.

Diamicron MR 60 Tablet, Glyciphage Gliclazide MR 60 Tablet, Glyclazide MR 60 Tablet, Glyzid MR 60 Tablet, Glizid MR 60 Tablet