Type 2 diabetes mellitus (to control high blood sugar in adults), Used when diet and exercise alone or single therapy is insufficient
How It Works
Glimepiride (a sulfonylurea) increases insulin release from the pancreas and helps lower blood glucose. Metformin (a biguanide) reduces glucose production in the liver and improves insulin sensitivity. Together they improve fasting and post‑meal sugar control.
Directions for Use
Take exactly as prescribed by your doctor. Usually taken once daily with breakfast or the first main meal; swallow whole with water. Metformin-containing tablets are best taken with food to reduce stomach upset; do not skip meals to reduce risk of low sugar.
Side Effects
Hypoglycaemia (low blood sugar), nausea, vomiting, diarrhoea, abdominal discomfort, loss of appetite, headache, dizziness, taste disturbance
Warnings & Precautions
Risk of hypoglycaemia (especially with missed meals, alcohol, heavy exercise); monitor blood glucose regularly. Metformin may rarely cause lactic acidosis—risk increases with kidney disease, severe dehydration, severe infection, shock, or excessive alcohol. Not recommended in severe renal impairment; kidney function should be assessed before and during therapy. Inform doctor before surgery or iodinated contrast imaging—metformin may need to be stopped temporarily. Use caution in liver disease and in elderly patients.
Drug Interactions
Habit Forming
No
ManufacturerKnoll Healthcare Pvt Ltd
BrandKnoll Healthcare Pvt Ltd
Alcohol (increases risk of hypoglycaemia and lactic acidosis), insulin/other antidiabetics (additive hypoglycaemia), beta-blockers (mask hypoglycaemia symptoms), corticosteroids and thiazide diuretics (raise blood sugar), ACE inhibitors (may increase hypoglycaemic effect), fluoroquinolones (glucose disturbances), cimetidine and other drugs affecting kidney tubular secretion (increase metformin levels), iodinated contrast media (risk of kidney injury/lactic acidosis)
Storage Instructions
Store below 25°C in a cool, dry place away from moisture and direct light. Keep out of reach of children.
Substitutes
Amaryl M 1 Tablet, Glycomet-GP 1 Tablet, Glimy M 1 Tablet, Glime-M 1 Tablet, Glimet 1 Tablet
Frequently Asked Questions
What is this medicine used for?
Type 2 diabetes mellitus (to control high blood sugar in adults), Used when diet and exercise alone or single therapy is insufficient
What are the side effects?
Hypoglycaemia (low blood sugar), nausea, vomiting, diarrhoea, abdominal discomfort, loss of appetite, headache, dizziness, taste disturbance
How does this medicine work?
Glimepiride (a sulfonylurea) increases insulin release from the pancreas and helps lower blood glucose. Metformin (a biguanide) reduces glucose production in the liver and improves insulin sensitivity. Together they improve fasting and post‑meal sugar control.
How should I use this medicine?
Take exactly as prescribed by your doctor. Usually taken once daily with breakfast or the first main meal; swallow whole with water. Metformin-containing tablets are best taken with food to reduce stomach upset; do not skip meals to reduce risk of low sugar.
How should I store this medicine?
Store below 25°C in a cool, dry place away from moisture and direct light. Keep out of reach of children.
Do I need a prescription for this product?
Yes, this product requires a valid prescription (Rx). Upload it during checkout when prompted.
Can prices or availability change?
Yes. Prices and availability can change based on inventory and serviceability. The latest details are shown at checkout.
How do I place an order?
Select a variant, add to cart, enter delivery address, upload prescription if required, and pay securely.
Manufacturer & Brand
Brand:Knoll Healthcare Pvt Ltd
Manufacturer:Knoll Healthcare Pvt Ltd
HSN Code:30049064
Alternatives
Alternatives are suggested by pharmacists after reviewing your order and prescription.
Disclaimer: Product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalized guidance.
Sources: Manufacturer labeling, CDSCO/Indian drug labeling norms, established medical literature (standard pharmacology references)