Glimiscore-M 0.5 Tablet

Glimiscore-M 0.5 Tablet contains Glimepiride 0.5 mg + Metformin hydrochloride (strength unknown). Prescription required.

Type 2 diabetes mellitus (adult) when diet and exercise alone are insufficient; used to improve glycaemic control.

Glimepiride (a sulfonylurea) stimulates the pancreas to release insulin and improves peripheral insulin sensitivity. Metformin reduces glucose production in the liver and decreases intestinal glucose absorption while improving insulin sensitivity.

Take orally as advised by a doctor, preferably with meals to reduce stomach upset and risk of low sugar. Swallow tablet whole with water; do not crush/chew unless advised. Monitor blood glucose regularly and follow diet/exercise plan.

Hypoglycaemia, nausea, vomiting, diarrhoea, abdominal pain, loss of appetite, metallic taste, dizziness, headache, weight gain, skin rash

Risk of hypoglycaemia (more likely with missed meals, excess exercise, alcohol, elderly, or kidney/liver impairment). Metformin may rarely cause lactic acidosis—seek urgent care for rapid breathing, severe weakness, muscle pain, unusual sleepiness, or abdominal discomfort. Use with caution/avoid in severe renal impairment, severe liver disease, dehydration, severe infection, hypoxia, or alcoholism. Temporarily stop metformin before and after iodinated contrast studies or major surgery as advised. Regularly monitor kidney function, liver function, and vitamin B12 with long-term use.

Alcohol (increases hypoglycaemia/lactic acidosis risk), insulin/other antidiabetics (additive hypoglycaemia), beta-blockers (mask hypoglycaemia symptoms), corticosteroids/thiazide diuretics (raise glucose), ACE inhibitors (may enhance hypoglycaemia), fluoroquinolones (glucose disturbances), rifampicin (reduces effect), azole antifungals and macrolides (may increase sulfonylurea effect), iodinated contrast media (lactic acidosis risk with metformin), cimetidine (increases metformin levels)

Store below 25°C in a dry place, protected from moisture and light. Keep in original blister pack and out of reach of children.

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