Preega M 75MG Cap

Capsule

Neuropathic pain (nerve pain) associated with diabetic neuropathy, post-herpetic neuralgia, peripheral neuropathy; vitamin B12 deficiency–related neuropathy (as advised by doctor).

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the CNS, reducing release of excitatory neurotransmitters and thereby decreasing nerve pain. Methylcobalamin is an active form of vitamin B12 that supports myelin sheath repair and nerve regeneration, helping improve neuropathic symptoms when B12 deficiency contributes.

Capsule for oral use. Take exactly as prescribed, preferably at the same time each day; may be taken with or without food. Swallow whole with water; do not crush or open. Do not stop suddenly—dose should be tapered under medical advice.

Dizziness, sleepiness (somnolence), blurred vision, dry mouth, weight gain, peripheral edema (swelling), constipation, fatigue, difficulty in concentration

May cause dizziness and drowsiness—avoid driving or operating machinery until you know the effect. Do not stop abruptly (risk of withdrawal symptoms and rebound pain). Use with caution in kidney disease (dose adjustment may be needed) and in elderly (higher fall risk). Monitor for mood changes, depression or suicidal thoughts; seek help if they occur. Caution in heart failure/edema and in patients prone to substance misuse.

Alcohol and other CNS depressants (increased drowsiness), opioids (e.g., tramadol, morphine) and benzodiazepines (sedation/respiratory depression risk), antihistamines/sedatives (additive CNS depression), antidiabetic thiazolidinediones like pioglitazone/rosiglitazone (increased edema/weight gain), ACE inhibitors (rare increased risk of angioedema)

Store below 25°C in a cool, dry place away from moisture and direct light. Keep in original blister pack and out of reach of children.

Pregabalin + Methylcobalamin capsules (generic equivalents from other brands)