Startglim-M2 Forte Tab

Tablet

Type 2 diabetes mellitus (to control high blood sugar) when diet and exercise alone are not sufficient; used in patients requiring combination therapy.

Metformin reduces glucose production in the liver and improves the body’s sensitivity to insulin, lowering insulin resistance. Glimepiride stimulates the pancreas to release more insulin, helping reduce blood glucose levels, especially after meals.

Take by mouth as prescribed by a doctor, usually once daily with the main meal (often dinner/breakfast depending on regimen). Swallow whole with water; do not crush or chew if it is SR/ER. Follow diet/exercise plan and monitor blood glucose regularly.

Nausea, vomiting, diarrhoea, abdominal pain, loss of appetite, metallic taste, headache, dizziness, hypoglycaemia (sweating, tremor, palpitations), weight gain

Risk of hypoglycaemia (higher with missed meals, alcohol, strenuous exercise, elderly); carry glucose/sugar. Metformin can rarely cause lactic acidosis—risk increases with kidney impairment, dehydration, severe infection, heart/respiratory failure, or heavy alcohol use. Avoid/use with caution in renal or hepatic impairment; kidney function monitoring recommended. Temporarily stop metformin before/after iodinated contrast imaging and major surgery as advised by doctor. Long-term metformin may cause vitamin B12 deficiency; consider periodic monitoring.

Alcohol (increases risk of hypoglycaemia/lactic acidosis), iodinated contrast media, insulin/other antidiabetics (additive hypoglycaemia), beta-blockers (may mask hypoglycaemia symptoms), corticosteroids and thiazide/loop diuretics (may raise glucose), ACE inhibitors (may enhance hypoglycaemia), rifampicin (may reduce glimepiride effect), azole antifungals/macrolides/fluoroquinolones (may alter glucose control), cimetidine (may increase metformin levels)

Store below 25°C in a dry place, protected from moisture and light. Keep out of reach of children.

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