Type 2 diabetes mellitus in adults when diet and exercise alone or single therapy is insufficient; helps control blood glucose levels.
How It Works
Glimepiride (a sulfonylurea) increases insulin release from the pancreas and improves insulin action. Metformin (a biguanide) reduces glucose production in the liver and improves insulin sensitivity, lowering blood sugar without usually causing hypoglycaemia when used alone.
Directions for Use
Take by mouth as prescribed, usually once or twice daily with meals (preferably with breakfast and/or main meals) to reduce stomach upset and risk of low sugar. Swallow tablet with water; do not skip meals. Dose is individualized based on blood glucose; do not self-adjust.
Side Effects
Hypoglycaemia, nausea, vomiting, diarrhoea, abdominal pain, loss of appetite, metallic taste, headache, dizziness, weight gain
Warnings & Precautions
Risk of hypoglycaemia (higher with missed meals, alcohol, heavy exercise, elderly, kidney/liver impairment). Metformin may rarely cause lactic acidosis—seek urgent care for rapid breathing, severe weakness, drowsiness, abdominal pain. Use caution/avoid in severe renal impairment, severe liver disease, alcohol misuse, dehydration, severe infection, shock, or hypoxia states; withhold around major surgery or iodinated contrast procedures as advised. Monitor kidney function, HbA1c, and blood glucose regularly.
Drug Interactions
Alcohol (increases hypoglycaemia and lactic acidosis risk), insulin/other antidiabetics (additive hypoglycaemia), sulfonamide antibiotics, fluoroquinolones, macrolides (may alter glucose), beta-blockers (mask hypoglycaemia), corticosteroids and thiazide diuretics (raise glucose), ACE inhibitors (may enhance glucose-lowering), iodinated contrast media (lactic acidosis risk with metformin), cimetidine (raises metformin levels)
Storage Instructions
Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.
Substitutes
Glimy M 1 Tablet, Amaryl M 1 Tablet, Glimepiride+Metformin 1/500 Tablet (generic), Glycomet-GP 1/500 Tablet, Gemer M1 Tablet
Frequently Asked Questions
What is this medicine used for?
Type 2 diabetes mellitus in adults when diet and exercise alone or single therapy is insufficient; helps control blood glucose levels.
What are the side effects?
Hypoglycaemia, nausea, vomiting, diarrhoea, abdominal pain, loss of appetite, metallic taste, headache, dizziness, weight gain
How does this medicine work?
Glimepiride (a sulfonylurea) increases insulin release from the pancreas and improves insulin action. Metformin (a biguanide) reduces glucose production in the liver and improves insulin sensitivity, lowering blood sugar without usually causing hypoglycaemia when used alone.
How should I use this medicine?
Take by mouth as prescribed, usually once or twice daily with meals (preferably with breakfast and/or main meals) to reduce stomach upset and risk of low sugar. Swallow tablet with water; do not skip meals. Dose is individualized based on blood glucose; do not self-adjust.
How should I store this medicine?
Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.
Do I need a prescription for this product?
Yes, this product requires a valid prescription (Rx). Upload it during checkout when prompted.
Can prices or availability change?
Yes. Prices and availability can change based on inventory and serviceability. The latest details are shown at checkout.
How do I place an order?
Select a variant, add to cart, enter delivery address, upload prescription if required, and pay securely.
Manufacturer & Brand
Brand:Intas Pharmaceuticals Ltd
Manufacturer:INTAS PHARMACEUTICALS`
HSN Code:30049099
Alternatives
Alternatives are suggested by pharmacists after reviewing your order and prescription.
Disclaimer: Product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalized guidance.
Sources: Manufacturer labeling, established medical literature, standard pharmacology references, Indian regulatory/pack labeling information