Oflotas Infusion

Oflotas Infusion contains Ofloxacin (200mg). Prescription required.

Treatment of susceptible bacterial infections such as urinary tract infections, respiratory tract infections, skin and soft tissue infections, gastrointestinal infections (including enteric fever/typhoid where appropriate) and other systemic infections when IV therapy is required

Ofloxacin is a fluoroquinolone antibiotic. It inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, blocking DNA replication and repair, leading to bacterial cell death.

For intravenous infusion only; administer by slow IV infusion as prescribed by the physician. Dose and duration depend on infection type and kidney function. Do not give as IV bolus or intramuscular injection; ensure compatibility with IV fluids and avoid mixing with incompatible medicines in the same line.

nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, insomnia, rash, injection-site pain/phlebitis, elevated liver enzymes

Use only for bacterial infections; inappropriate use increases resistance. Fluoroquinolones may cause tendonitis/tendon rupture, peripheral neuropathy, CNS effects (seizures, confusion), QT prolongation/arrhythmias, severe hypersensitivity reactions and Clostridioides difficile-associated diarrhea—stop and seek care if symptoms occur. Use with caution in epilepsy/CNS disorders, myasthenia gravis, heart rhythm disorders, and in elderly. Adjust dose in renal impairment. Avoid unnecessary sun/UV exposure (photosensitivity).

Drugs that prolong QT (e.g., amiodarone, sotalol, macrolides, antipsychotics), corticosteroids (increased tendon rupture risk), antidiabetic agents/insulin (dysglycemia), warfarin (may increase INR/bleeding), NSAIDs (may increase CNS stimulation/seizure risk), probenecid/cimetidine (may reduce renal clearance)

Store below 25°C; protect from light. Do not freeze. Keep in original container; use only if solution is clear and container intact.

Zanocin IV Infusion, Oflox IV Infusion, Oflocin IV Infusion, Tarivid IV Infusion, Oflox-200 IV Infusion