Aciloc Injection

Composition of Aciloc Injection

Aciloc Injection contains Ranitidine (as Ranitidine Hydrochloride) 25 mg/mL injection (2 mL ampoule = 50 mg). It belongs to the H2 receptor antagonist class of medicines.

Uses of Aciloc Injection

• Treatment and prevention of acid-related disorders such as peptic ulcer disease
• gastroesophageal reflux disease (GERD)
• erosive esophagitis
• Zollinger–Ellison syndrome; prophylaxis of stress ulcers and aspiration (acid) pneumonitis in peri-operative settings (as prescribed).

Key benefits

• Reduces stomach acid secretion
• Relieves heartburn and reflux symptoms
• Promotes healing of gastric/duodenal ulcers
• Helps prevent stress-related mucosal bleeding in hospital settings

How Aciloc Injection works

Ranitidine is an H2-receptor antagonist that reduces gastric acid secretion by blocking histamine H2 receptors on gastric parietal cells. This lowers both basal and stimulated acid output, helping relieve symptoms and promote ulcer healing.

How to take Aciloc Injection

For intravenous or intramuscular use only; to be administered by a healthcare professional. Dose and frequency depend on indication and patient factors; may be given as slow IV injection/IV infusion or IM injection. Follow the treating doctor’s instructions; do not self-administer.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe loose motions or constipation and disturb the body's salt balance. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Aciloc Injection

Most side effects of Aciloc are mild and settle as the body adjusts. Reported side effects include:

• Headache
• dizziness
• diarrhea
• constipation
• nausea
• abdominal pain
• rash
• injection site pain
• increased liver enzymes

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Aciloc Injection

Warnings and precautions

Prescription-only injectable. Use with caution in renal impairment (dose adjustment may be needed) and in patients with acute porphyria. Rare: hypersensitivity reactions, bradycardia/hypotension with rapid IV administration, blood dyscrasias, hepatic dysfunction. If alarm symptoms (weight loss, recurrent vomiting, GI bleeding) are present, rule out gastric malignancy. Note: Ranitidine products have been subject to regulatory actions/withdrawals in many markets due to NDMA impurity concerns—use only if supplied/approved per current local regulatory guidance and hospital policy.

Do not take Aciloc if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Magnesium-containing antacids are avoided in significant kidney disease.

Interactions with other medicines

Warfarin (INR changes reported), procainamide (increased levels), metoprolol (may increase exposure), drugs requiring acidic gastric pH for absorption (e.g., ketoconazole, itraconazole, atazanavir), sucralfate (may reduce absorption if given together)

How to store Aciloc Injection

Store below 25°C, protect from light, do not freeze. Keep ampoules in original carton until use; use immediately after opening and discard any unused portion.

Expert advice for Aciloc Injection

Take it after meals and at bedtime when symptoms are worst. Avoid late heavy meals, and raise the head of your bed if symptoms wake you at night.

Manufacturer and class

Manufacturer:

CADILA PHARMA

Therapeutic class:

Antiulcerant / Antacid (Anti-secretory)

Drug class:

H2 receptor antagonist