Dgson M 10/500 Tablet

Composition of Dgson M 10/500 Tablet

Dgson M 10/500 Tablet contains Dapagliflozin 10 mg + Metformin Hydrochloride 500 mg (usually sustained/extended release). It belongs to the SGLT2 inhibitor + Biguanide class of medicines.

Uses of Dgson M 10/500 Tablet

Type 2 diabetes mellitus (to improve glycaemic control) as an adjunct to diet and exercise; may be used when dual therapy is required or when not controlled on single agent

Key benefits

• Lowers blood glucose in type 2 diabetes
• Improves insulin sensitivity and reduces liver glucose output
• Promotes urinary glucose excretion and may aid weight reduction
• Lowers fasting and post-meal glucose
• May reduce blood pressure slightly due to mild diuretic effect

How Dgson M 10/500 Tablet works

Dapagliflozin is an SGLT2 inhibitor that reduces glucose reabsorption in the kidneys, increasing urinary glucose excretion and lowering blood sugar. Metformin decreases hepatic glucose production and improves insulin sensitivity, reducing glucose levels.

How to take Dgson M 10/500 Tablet

Oral tablet. Take exactly as prescribed by the doctor, usually once daily with food (especially if metformin is SR/ER) to reduce stomach upset. Swallow whole; do not crush/chew sustained/extended-release tablets. Maintain adequate hydration.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause dehydration and a fall in blood pressure. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Dgson M 10/500 Tablet

Most side effects of Dgson M 10/500 are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• diarrhoea
• abdominal discomfort
• decreased appetite
• headache
• increased urination
• thirst
• genital yeast infection
• urinary tract infection
• dizziness

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Dgson M 10/500 Tablet

Warnings and precautions

Not for type 1 diabetes or diabetic ketoacidosis. Risk of lactic acidosis with metformin (higher risk in severe kidney impairment, dehydration, sepsis, heavy alcohol use); stop and seek help for severe weakness, rapid breathing, abdominal pain. SGLT2 inhibitors can cause genital infections, dehydration/low BP, and (rare) ketoacidosis even with normal sugars—seek care for nausea/vomiting, abdominal pain, rapid breathing. Monitor kidney function before and during therapy; not recommended in severe renal impairment. Hold before major surgery or during acute illness/poor intake; avoid dehydration. Use caution in elderly and with diuretics. Hypoglycaemia risk increases if used with insulin or sulfonylureas.

Do not take Dgson M 10/500 if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Insulin and sulfonylureas (increased hypoglycaemia risk), diuretics (increased dehydration/hypotension risk), ACE inhibitors/ARBs and NSAIDs (kidney function risk when combined with dehydration), iodinated contrast media (increase lactic acidosis risk—temporary discontinuation of metformin may be needed), alcohol (increases lactic acidosis risk), carbonic anhydrase inhibitors like topiramate (may increase acidosis risk), digoxin (metformin may increase levels—monitor)

How to store Dgson M 10/500 Tablet

Store below 25°C in a dry place, protected from moisture and light. Keep in original blister pack and out of reach of children.

Expert advice for Dgson M 10/500 Tablet

Take it in the morning so the extra urine does not disturb your sleep. Keep up your fluid intake and maintain genital hygiene. Tell any doctor treating you for an acute illness that you take this medicine. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

Manufacturer and class

Manufacturer:

UNISON PHARMACEUTICALS

Therapeutic class:

Antidiabetic

Drug class:

SGLT2 inhibitor + Biguanide