Glimibrit M 0.5 mg Tablet

Composition of Glimibrit M 0.5 mg Tablet

Glimibrit M 0.5 mg Tablet contains Glimepiride 0.5 mg + Metformin (strength unknown). It belongs to the Sulfonylurea + Biguanide class of medicines.

Uses of Glimibrit M 0.5 mg Tablet

Type 2 diabetes mellitus (adult) to control high blood sugar when diet and exercise alone are not sufficient

Key benefits

• Lowers fasting and post-meal blood sugar
• Improves insulin secretion and sensitivity
• Helps achieve better HbA1c control
• May reduce diabetes-related complications with good control

How Glimibrit M 0.5 mg Tablet works

Glimepiride (a sulfonylurea) increases insulin release from the pancreas and improves peripheral glucose utilization. Metformin (a biguanide) reduces glucose production in the liver and improves insulin sensitivity, lowering blood glucose without usually causing hypoglycaemia on its own.

How to take Glimibrit M 0.5 mg Tablet

Take by mouth as advised by doctor, usually once daily with or just after the first main meal to reduce stomach upset and risk of low sugar. Swallow tablet whole with water; do not crush/chew unless advised. Follow diet, exercise, and regular blood glucose monitoring.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Glimibrit M 0.5 mg Tablet

Most side effects of Glimibrit M are mild and settle as the body adjusts. Reported side effects include:

• Hypoglycaemia
• nausea
• vomiting
• diarrhoea
• abdominal pain
• loss of appetite
• metallic taste
• headache
• dizziness
• weight gain
• skin rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Glimibrit M 0.5 mg Tablet

Warnings and precautions

Risk of hypoglycaemia (more with missed meals, alcohol, strenuous exercise, elderly, kidney/liver impairment); metformin may rarely cause lactic acidosis—seek urgent care for severe weakness, rapid breathing, persistent vomiting, or abdominal pain. Use caution/avoid in significant renal impairment, severe liver disease, dehydration, severe infection, shock, or hypoxia; temporarily stop metformin before/after iodinated contrast or major surgery as advised. Monitor kidney function, HbA1c, and vitamin B12 (long-term metformin).

Do not take Glimibrit M if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Alcohol (increases hypoglycaemia and lactic acidosis risk), insulin/other antidiabetics (additive hypoglycaemia), sulfonamide antibiotics, fluoroquinolones, beta-blockers (mask hypoglycaemia), corticosteroids and thiazide diuretics (raise glucose), ACE inhibitors (may increase hypoglycaemia), rifampicin (reduces effect), cimetidine and other OCT2/MATE inhibitors (increase metformin levels), iodinated contrast media

How to store Glimibrit M 0.5 mg Tablet

Store below 25°C in a cool, dry place away from light and moisture. Keep in original blister pack and out of reach of children.

Expert advice for Glimibrit M 0.5 mg Tablet

Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

Manufacturer and class

Manufacturer:

ELBRIT LIFE SCIENCES PVT LTD

Therapeutic class:

Antidiabetic

Drug class:

Sulfonylurea + Biguanide